DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15270 and LOC100489387

DIOPT Version :9

Sequence 1:	NP_609738.1	Gene:	CG15270 / 34886	FlyBaseID:	FBgn0028879	Length:	1338	Species:	Drosophila melanogaster
Sequence 2:	XP_031756607.1	Gene:	LOC100489387 / 100489387	-ID:	-	Length:	730	Species:	Xenopus tropicalis

Alignment Length:	713	Identity:	165/713 - (23%)
Similarity:	250/713 - (35%)	Gaps:	233/713 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 LHGRAAVAEG-----QSIVATWQESGLITQVFPLHEPSSLTQ--LQTHWV--KQIFAPQPLDDIA 290
            ||..|.:..|     |.::.|    .:....||||.....|:  |:..|.  :.|...||:::|.
Frog   113 LHNTAILFRGKEEKLQDLIKT----QVFEAAFPLHTRKDQTREGLKKKWARWRDIIYVQPIEEIR 173

  Fly   291 AYFGVKVALYFAWLGHYTCALGVPAVFGTILY-------------------------------CI 324
            ||:|.||||||||||.||..|...||.|.|::                               |.
Frog   174 AYYGEKVALYFAWLGWYTIMLLYAAVVGLIVFFYGFVHFDNSQISQEICRANNTLMCPLCDQNCP 238

  Fly   325 LWGKGQTA---------QDMGHVLFSLFNVAWASLYLEAWKRYSVELAFRWGTLSTPPELLEPPR 380
            .|....|.         .:.|.|.|::|...||:::||.|||........|.
Frog   239 YWPLSDTCTYAKVTHLFDNEGTVFFAMFMAVWATVFLELWKRARANTVSGWN------------- 290

  Fly   381 PLYKGPLEENNVTGRL--EPK------EAPAWQRRAF---RYLVSFPIIGCC-LCVVFAVMFLML 433
             ||....:|..:...|  :|:      |...|:..|.   ..:|...:||.. ..|::.|:..:.
Frog   291 -LYNWDEDEEELALELINDPECTIKKHEHSYWRFMAVLLGAAVVIAVLIGIAQALVIYRVVVTVS 354

  Fly   434 RFQDWWDSKLPEESVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKV 498
            ..:..|:......:....:|  ..||....|.:|.:....:|.:|.:.|..|..::.||....||
Frog   355 FMRSSWEFLREHANTAAVMS--GAVLHYLTIVIMTKVNRVIAGYLCNLEKPRTFTERENSFTTKV 417

  Fly   499 ALFQFVNSFLSLFYIAFYLRDEEKLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKLSFNMWG 563
            ..||||..|.||||:||:|               .|:           ||..:|:|.|
Frog   418 FTFQFVTHFSSLFYVAFFL---------------GRR-----------YFSYKWRLMK------- 449

  Fly   564 ALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRN--IGQAEIESSLYKYDGTFSD 626
                                 :.:....|............:.|  :|...:.|       .|.:
Frog   450 ---------------------DRRCRVHGEDGSEDSAAECWRTNYRLGAVHVFS-------LFDE 486

  Fly   627 HLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVAN-IGTWQNALSI 690
            .|||::|..:..:|.||||||.|.|.:||::|||.||.|:..: ||.|..|.|| ||.|...|..
Frog   487 FLEMVIQYSFTTIFVAAFPLAPVLAFLNNVLEIRLDAIKMTRL-QRRFVPRKANDIGIWLQVLEA 550

  Fly   691 LSLAAVIVNCALIG----------------------------LSG------------------QV 709
            :.:.|||.|..:|.                            |||                  ||
Frog   551 VGVLAVITNGLVIAVTSDFIPRLIYLYVYGPCANGNTEGINCLSGYVDSSLSVFYTKDFEDLTQV 615

  Fly   710 SR-LWPGLTT----------------------AQTIILIVTLEHIMLGLRQALTWLLPELPSWLA 751
            || |:..:|.                      |..:..::..||:.:.::....|.:|::|.
Frog   616 SRSLYTNVTECRYRDYRSAADYSFSTQFWHIFAARLGFLIVFEHVAVCIKFVAAWFVPDIPQ--- 677

  Fly   752 AEIARAEHCRREMQCKGTSPRPTPPTPQSTTSTQPEQEGPGGLQMESGANTTRDQSMESQVAE 814
                |.|:...:|:.:..         ....|..||:...  ...|...|:.||..|:.::.|
Frog   678 ----RVENYNLDMKKQHL---------LEELSMMPEESDE--YHKEGSPNSYRDFLMDDRMIE 725

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	138/592 (23%)
LOC100489387	XP_031756607.1	Anoct_dimer	27..169	CDD:406563	15/59 (25%)
LOC100489387	XP_031756607.1	Anoctamin	172..689	CDD:398306	140/601 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010