Protein Alignment CG15270 and ano10

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_002937896.1
• Gene: ano10 / 100487513
• XenbaseID: XB-GENE-955754
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 711
• Identity: 224/711 - (31%)
• Similarity: 356/711 - (50%)
• Gaps: 88/711 - (12%)

  Fly   110 VVIEFPEDAPDEALRWLLARIR-SQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAAEEARL 173
            ||||..:||.:|...||:.:|| .:...|..||::.....:.....:.|......|...||...:
 Frog    19 VVIELAKDAKEETREWLVKKIRDKKKDGGTQLLIKPLVISNDEEYIYVVGGSTKRLLLGAESVGM 83

  Fly   174 PKRLRPDLGGALREFTTRESHCFQQLRGDVGSTALFTSQERQWLVLQVLQGLRAGCSDIEALHG- 237
            .|..   :.|:::.|.......::....| |...| :..:.|:::...|..|||  .|.:.:.|
 Frog    84 VKEC---IDGSMKPFIYSNRKEYKDWTED-GENFL-SMADCQYIIKYELDNLRA--QDEKNIPGY 141

  Fly   238 -RAAVAEGQSIVATWQESGLITQVFPLHEPSSLTQLQTHWVKQI-FAPQPLDDIAAYFGVKVALY 300
             .:.:..|:||....:.||::.||||||:...|.:|:..|..:| .|.||:|.|..|||..:.||
 Frog   142 PNSKLYPGKSIFRRLKTSGIMIQVFPLHDKEELKRLRHQWYLRIKLAFQPIDQIQHYFGDTLGLY 206

  Fly   301 FAWLGHYTCALGVPAVFGTILYCILWGKGQTAQDMG-HVLFSLFNVAWASLYLEAWKRYSVELAF 364
            ||:|.::|.||...|:.|...|...|      :|.. :|:|:.||:.|:::.||.|||.|..:.:
 Frog   207 FAFLEYFTMALIPMALIGIPYYFFDW------EDYDKYVIFATFNLVWSTVILEVWKRLSSAMTY 265

  Fly   365 RWGTLSTPPELLEPPRPLYKGPLEENNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCLCVVFAVM 429
            |||:|....: .|.|||.:.|.|..|.||||.||..: :::|:...||||.|.:  |:|:..|:.
 Frog   266 RWGSLIMKRK-FEEPRPGFHGVLGINPVTGRKEPIYS-SFKRQLRIYLVSVPFV--CVCLYLAIY 326

  Fly   430 FLMLRFQ-DWWDSKLPEE---SVLCCLSVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKY 490
            .:|:.|. :.|.....:|   :....|..:|.::.|..|.:::..|...|.:|...||:||:|.|
 Frog   327 VMMIYFDLEHWALAYHQEQQSTFSNLLLYVPSIIYAVVIEILNRIYKIAAEFLTSWENHRLESSY 391

  Fly   491 ENHLIAKVALFQFVNSFLSLFYIAFYLRDEEKLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLA 555
            :|||:.||.:|..||.|.|||||||.:.|.:.|::.||.|||:.||:....|:.:||:|::....
 Frog   392 QNHLVLKVLVFNIVNCFASLFYIAFVMCDMKLLRQSLATLLITSQILNQFVEALLPYWLQKRSSR 456

  Fly   556 KLSFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKY 620
            |:                           :.|.:|....|.....|        |..:|..:..|
 Frog   457 KI---------------------------KKKVKSLNVDTDYTLLE--------QIHLEKDMDTY 486

  Fly   621 DGTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQ 685
            .|||.|:||:.:..|||.|||..:|||.:.|::|||.|:.|||.|:..|::|||.|..||||.|.
 Frog   487 LGTFDDYLELFLLFGYVSLFSCVYPLAAIFAVLNNLTEMYSDALKMCRVYKRPFSQPSANIGVWM 551

  Fly   686 NALSILSLAAVIVNCALIGLSGQVSRLWPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWL 750
            .|...:.:.||:.||.|:|:|.|||.|:.. :....|:.:..:||.:|.|:..|.:::|:.|..:
 Frog   552 LAFETMGIIAVVTNCTLLGMSSQVSTLFQD-SKRDLILTVAAIEHALLALKFILAFVIPDKPYDI 615

  Fly   751 AAEIARAEHCRREMQCKGTSPRPTPPTPQSTTSTQPEQEGPGGLQME-SGANTTRDQSMES 810
            ..::||.|.                   :|..:.:..|      ||: |..:.|.|::|:|
 Frog   616 QVKLARLEF-------------------ESMEALKKNQ------QMKLSSESLTDDEAMDS 651

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	164/473 (35%)
ano10	XP_002937896.1	Anoctamin	195..621	CDD:367984	162/471 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	1	1.000	-	-		FOG0001419
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920