Protein Alignment CG15270 and ano6

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_002932853.1
• Gene: ano6 / 100486935
• XenbaseID: XB-GENE-982324
• Length: 909
• Species: Xenopus tropicalis
• Alignment Length: 932
• Identity: 210/932 - (22%)
• Similarity: 337/932 - (36%)
• Gaps: 326/932 - (34%)

  Fly    49 DDFTDDNNFESNLRRRKGKII---SCAKETIENAS--RQLRRKVPYAGHLMTPRRLWLNKIPTQC 108
            |:..|...|..|.||....::   ...||.|...|  :|.:::..|..:|: ...|.|....:..
 Frog    55 DENLDSLYFTDNQRRIDYVLVYEDETMKEHIAKKSFLKQKKKRQAYESNLI-KSGLHLEATRSVS 118

  Fly   109 DVVIEFPE-DAPDEAL----RWLLARIRSQPPAGLGLLVQVKAHESTRRNAFYVSAPVNVLFKAA 168
            |..|.|.: .||.|.|    ..:..::..||.       .::.|:|. .|.|      ..:|:.:
 Frog   119 DGKIIFVKVHAPWEVLCTYAEVMHIKLPLQPN-------DLRKHQSA-FNCF------TKIFRVS 169

  Fly   169 EEARLPKRLRPDLGGALREFTTRESHCFQQLRGD----VGSTALFTSQERQWLVLQVLQGLRAGC 229
            |:.     ::|:     :||.|..   |::.|.|    ......||...|..:|..:|..:....
 Frog   170 EDI-----IKPE-----QEFFTAP---FEKDRIDDFYIQDKETFFTPATRSRIVHFILSRVEYAI 221

  Fly   230 SDIEALHGRAAVAEGQSIVATWQESGLITQVFPLHE------------PSSLTQLQTHWVK--QI 280
            .:.....|          :....:||:....||||:            ||....|...|..  .|
 Frog   222 KENVKKFG----------INKLLDSGIYKAAFPLHDCNFNAVSVDSRCPSERYILYKQWAHPFSI 276

  Fly   281 FAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILYCILWG-KGQTA------------ 332
            ...||||.:..|:|.||.:||||||.||..|.|.||.|  :.|.|:| |.|..
 Frog   277 LKFQPLDLVRKYYGEKVGIYFAWLGFYTRMLIVAAVVG--VACFLYGVKSQETCTWSKEVCDPSI 339

  Fly   333 --------------------------------QDMGHVLFSLFNVAWASLYLEAWKRYSVELAFR 365
                                            ...|.::|::|...|.:|:||.|||...||.:.
 Frog   340 GGSIIMCPQCDKACNYWYLNITCESSKKLCIFDSFGTLVFAVFMGIWVTLFLEFWKRRQAELEYE 404

  Fly   366 WGTLSTPPELL---EPPRPLYKGP---LEENNVTGRLEPKEAPAWQRRAFRYLVSFPIIGCCL-- 422
            |.|:    |.|   |.|.|.|:..   :.:|.:|.:.|.              |.:...|.||
 Frog   405 WDTV----EFLEQEEQPLPEYEAKCTHVVKNRITQQEEH--------------VPYTAFGKCLRV 451

  Fly   423 -CVVFAVMFLML----------------------------------RFQDWWDSKLPEESVLCCL 452
             |...||.|.:|                                  ..|.:   ..|:.:.....
 Frog   452 TCCTSAVFFWILLIVASVVGIIVYRLSVFLVFSATLPRAVNGTNVEAIQKY---LTPQTATTITA 513

  Fly   453 SVIPKVLLAGAITLMDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAFY- 516
            |:|..::    |.|::..|.|:|:.:.|.|..|.:::|||.|..|:.||||||.:.|.|||||:
 Frog   514 SIISFII----IMLLNMLYEKVAIIITDFELPRTRTEYENSLTTKMFLFQFVNYYSSCFYIAFFK 574

  Fly   517 ----------------LRDEE--------KLKEQLAGLLISRQIIGNLRESAIPYFLEQWKLAKL 557
                            .|:||        :|..||..::..:.|..|::|..:|:
 Frog   575 GKIVGYPGDPVYWFGKYRNEECDPGGCLLELTTQLTIIMGGKAIWNNIQEILVPW---------- 629

  Fly   558 SFNMWGALSPTQNVTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYD- 621
                      .:|:.                        |:...|.||..:.:.|.:..|....
 Frog   630 ----------VKNLI------------------------SRCRSSGSKAVLPRWEADYLLQPAGK 660

  Fly   622 -GTFSDHLEMLVQMGYVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQ 685
             |.|.::|||::|.|:|.||.|:||||.|.||:|||:|||.||:|:....:|...::..:||.||
 Frog   661 LGLFYEYLEMVIQFGFVTLFVASFPLAPVLALVNNLLEIRVDAWKITTQWRRMVPEKAQDIGAWQ 725

  Fly   686 NALSILSLAAVIVNCALIGL-SGQVSRL------------------------------------- 712
            ..:..:::.||:.|..:|.. |..:.||
 Frog   726 PIMEGVAILAVVTNAMIIAFTSDMIPRLVYYWSFSVPPYGNYTTNTMQGYINNTLSVFSVSDFQS 790

  Fly   713 --------W--------------PG-------------LTTAQTIILIVTLEHIMLGLRQALTWL 742
                    |              ||             :..|:...||| :|||:..::..:.::
 Frog   791 ESKPVAVNWFNPTVCRYRDFRYPPGHEHQYEHSVYYWHVVAAKLSFLIV-MEHIVYFVKFIIAYI 854

  Fly   743 LPELPSWLAAEIARAEHCRREM 764
            :|::.:....:|.|.::..:::
 Frog   855 IPDVSNETKDKIKREKYLTQKL 876

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	152/656 (23%)
ano6	XP_002932853.1	Anoct_dimer	62..282	CDD:374413	53/257 (21%)
		Anoctamin	285..869	CDD:367984	151/655 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920