Protein Alignment CG15270 and Ano2

DIOPT Version :9

• Sequence 1: NP_609738.1
• Gene: CG15270 / 34886
• FlyBaseID: FBgn0028879
• Length: 1338
• Species: Drosophila melanogaster
• Sequence 2: XP_008761521.2
• Gene: Ano2 / 100361584
• RGDID: 1591606
• Length: 979
• Species: Rattus norvegicus
• Alignment Length: 1034
• Identity: 220/1034 - (21%)
• Similarity: 380/1034 - (36%)
• Gaps: 359/1034 - (34%)

  Fly    42 GPRDGGEDDFTDDNNFESNLRRRKG----KIISCAKETIENASRQLR----------RKVPYA-- 90
            |||..|:.|  :.:...|.:.||:.    .:|:...:..|.||.:.|          |||.|.
  Rat    19 GPRLPGQRD--NSSLHPSQVSRRESSRDRSVINNYLDANEPASSEARLSRMHFHDNQRKVDYVLA 81

  Fly    91 ---------------GHLMT---------------PRRLWLNKIPTQCDVVIEFPEDAPDEALRW 125
                           ||.:.               |..:.|..:    |.:.|...:..||....
  Rat    82 YHYRKRGAHLGHGSPGHSLAVISNGETGKERHGGGPGDIELGPL----DALEEERREQRDEFEHN 142

  Fly   126 LLARIRSQPPAGLGLLVQVKAHESTRRNAFYV--SAPVNVLFKAAE--EARLPKRLRPDL--GGA 184
            |:|       |||.|   .|..||..:.:.:|  .||..||.:.||  :.::|.:...::  ||:
  Rat   143 LMA-------AGLEL---EKDLESKSQGSVFVRIHAPWQVLAREAEFLKIKVPTKKMYEIKAGGS 197

  Fly   185 LRE-------------------------------FTTRESHCFQQLRGDVGSTALFTSQERQWLV 218
            :.:                               |:..:.:.:.....|    |.|.:..|..:|
  Rat   198 IAKKFSAILQTLSSPLQPRVPEHSNNRMKNLSYPFSREKMYLYNIQEKD----AFFDNATRSRIV 258

  Fly   219 LQVLQGLRAGCSDIEALHGRAAVAEG-QSIVATWQESGLITQVFPLH---------EPSSLTQLQ 273
            .::|:  |..||       ||....| .|::|    :.:....:|||         :.:....|.
  Rat   259 HEILK--RTACS-------RANNTMGINSLIA----NNIYEAAYPLHDGEYDSPGDDMNDRKLLY 310

  Fly   274 THWVKQ--IFAPQPLDDIAAYFGVKVALYFAWLGHYTCALGVPAVFGTILY-------------- 322
            ..|.:.  .:..||:|.|..|||.|:.|||||||.||..|...:|.|.|::
  Rat   311 QEWARYGVFYKFQPIDLIRKYFGEKIGLYFAWLGLYTSFLIPSSVIGVIVFLYGCATIEEDIPSK 375

  Fly   323 ------------------CILWGKGQ---TAQ------DMGHVLFSLFNVAWASLYLEAWKRYSV 360
                              |..|....   ||:      :...|.||:|...||:::||.|||..:
  Rat   376 EMCDHQNAFTMCPLCDKSCDYWNLSSACGTARASHLFDNPATVFFSIFMALWATMFLENWKRLQM 440

  Fly   361 ELAFRW---GTLSTPPELLEPPRPLYK----------------GPLEENNVTGRLEPKEAPAWQR 406
            .|.:.|   |.........|..||.|:                ..||.|:.....:.::...|:.
  Rat   441 RLGYFWDLTGIEEEEERSQEHSRPEYETKVREKLLKESGKSAVQKLEANSPEDDEDDEDKLTWKD 505

  Fly   407 RAFRYLVSFPIIGCCLCVVFAVMFLMLRFQDWWD-----SKLPEESVLCCLSVIPKVLLAGAITL 466
            |...||::...|...:.:.|:::|.::.::....     :|....:|...::....::....|.:
  Rat   506 RFPGYLMNSVSILFMIALTFSIVFGVIVYRITTAAALSLNKATRSNVRVTVTATAVIINLVVILI 570

  Fly   467 MDEAYFKLAVWLNDRENYRLQSKYENHLIAKVALFQFVNSFLSLFYIAF-------------YLR 518
            :||.|..:|.||...|..:.:..:|..||.|..|.:|||::..:||:||             |:.
  Rat   571 LDEIYGAVAKWLTKIEVPKTEQTFEERLILKAFLLKFVNAYSPIFYVAFFKGRFVGRPGSYVYVF 635

  Fly   519 DEEKLKE------------QLAGLLISRQII-GNLRESAIPYFLEQWKLAKLSFNMWGALSPTQN 570
            |..:::|            ||:.:::.:|:| .|:.|..:|      ||.||
  Rat   636 DGYRMEECAPGGCLMELCIQLSIIMLGKQLIQNNIFEIGVP------KLKKL------------- 681

  Fly   571 VTRSLAEELATAEAELKAESTGTPTKSQQPESSSKRNIGQAEIESSLYKYDGTFSDHLEMLVQMG 635
             .|.|.:|....|::        |..|::||        |.:::.||..|.|...:::||::|.|
  Rat   682 -FRKLKDETEPGESD--------PDHSKRPE--------QWDLDYSLEPYTGLTPEYMEMIIQFG 729

  Fly   636 YVVLFSAAFPLAGVCALINNLMEIRSDAFKLAHVHQRPFGQRVANIGTWQNALSILSLAAVIVNC 700
            :|.||.|:||||.|.||:||::|:|.||.|.....:||...|..:||.|.:.||.:...:||:|.
  Rat   730 FVTLFVASFPLAPVFALLNNVIEVRLDAKKFVTELRRPDAVRTKDIGIWFDILSGIGKFSVIINA 794

  Fly   701 ALIGLSG-----------------------------QVSRL------------------------ 712
            .:|.::.                             .||:|
  Rat   795 FVIAVTSDFIPRLVYQYSYSHNGTLHGFVNHTLSFFNVSQLKEGTQPENSQFDQEVQFCRFKDYR 859

  Fly   713 ---------------WPGLTTAQTIILIVTLEHIMLGLRQALTWLLPELPSWLAAEI-------- 754
                           |..|:.....::|  .:::::.|...:.|::|::|:.::.:|
  Rat   860 EPPWAPNPYEFSKQYWSVLSARLAFVII--FQNLVMFLSVLVDWMIPDIPTDISDQIKKEKSLLV 922

  Fly   755 ---ARAEHCRREMQCKGTSPRPTPPTPQSTTSTQPEQEGPGGLQMESGANTTRDQSMES 810
               .:.||.:.::                  :.:|.|...||     |..:.|.::..|
  Rat   923 DFFLKEEHEKVKL------------------ADEPAQRSQGG-----GNRSRRSRAASS 958

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15270	NP_609738.1	Anoctamin	289..758	CDD:282414	144/638 (23%)
Ano2	XP_008761521.2	Anoct_dimer	68..325	CDD:406563	52/287 (18%)
		Anoctamin	328..917	CDD:398306	144/626 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1263362at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920