Protein Alignment vig and SERBP1

DIOPT Version :9

• Sequence 1: NP_523572.1
• Gene: vig / 34885
• FlyBaseID: FBgn0024183
• Length: 490
• Species: Drosophila melanogaster
• Sequence 2: NP_001018077.1
• Gene: SERBP1 / 26135
• HGNCID: 17860
• Length: 408
• Species: Homo sapiens
• Alignment Length: 519
• Identity: 156/519 - (30%)
• Similarity: 212/519 - (40%)
• Gaps: 160/519 - (30%)

  Fly     7 NRYELLFMDDDVSDPLDNLVAPTAAAAAAAAGKKKQPSAAAAA--ATKTTANKVANSNNKANAGS 69
            ||::.||  ||.|||.:.|        .||..|||:.......  ..|:.|...|.:|      |
Human    15 NRFDQLF--DDESDPFEVL--------KAAENKKKEAGGGGVGGPGAKSAAQAAAQTN------S 63

  Fly    70 NIGGPNAKKPNQAEKENKPNNALNKTDGKKFT--PSADNKQQQFNNNASSNYKQQGAPRQGGGAN 132
            |..|...:|.:|.:::|....::...|.|:.|  |.|              .|::|..|.|...:
Human    64 NAAGKQLRKESQKDRKNPLPPSVGVVDKKEETQPPVA--------------LKKEGIRRVGRRPD 114

  Fly   133 RTREFGSGQGQGQGQGGQQQRSVNFRQQNGNAETREQRNNRRNVRENVGAPDGQQS-------RP 190
            :         |.||:|    :.::.|.:  ....||:|..:....:..|   |:.|       ||
Human   115 Q---------QLQGEG----KIIDRRPE--RRPPRERRFEKPLEEKGEG---GEFSVDRPIIDRP 161

  Fly   191 YRGPGG-GPGAGG-DRPQRQNRNYDGQNRKREFDRQSGSDR------TGVKSIDKRDGAGSHNWG 247
            .||.|| |.|.|| .|...:...:|.:. ||||||.|||||      :|:|..|||.|:||||||
Human   162 IRGRGGLGRGRGGRGRGMGRGDGFDSRG-KREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWG 225

  Fly   248 SVKEAIDD--------VNKNES---ETNVT--NAEGGAKADESGTE-PQNE-QATAEEEAKELTL 297
            :||:.:.:        ::.|.|   ::|||  ..||......:.|| .:|| :...||..||:||
Human   226 TVKDELTESPKYIQKQISYNYSDLDQSNVTEETPEGEEHHPVADTENKENEVEEVKEEGPKEMTL 290

  Fly   298 DEWKA-QQGQRIKPTFNIRKAGEGEDTTQWKKMVVLTSNKKKENDSEEELEYDPALYPQRVGRQQ 361
            ||||| |...|.|..|||||..||.| .||||..||..:|.:|..:|:.:.......|......|
Human   291 DEWKAIQNKDRAKVEFNIRKPNEGAD-GQWKKGFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQ 354

  Fly   362 RVLDIQFNFNDGRRGGPGGFGGRGGRGGPRPGGFGGGPRSEGGNRDGGNREGGRDNREGGNRGPR 426
                ::.||.|..|.|.||.|||||||                       .|||.||
Human   355 ----LEINFGDLGRPGRGGRGGRGGRG-----------------------RGGRPNR-------- 384

  Fly   427 DGQQHNNEGGGSSAQNQRPPIDRRGPGNNQNNNQNSGPGPNKRFERQQNTAPKVNDERQFPTLA 490
                      ||                              |.::...:||.|:|...||.||
Human   385 ----------GS------------------------------RTDKSSASAPDVDDPEAFPALA 408

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
vig	NP_523572.1	HABP4_PAI-RBP1	217..319	CDD:282609	55/123 (45%)
SERBP1	NP_001018077.1	IHABP4_N	5..152	CDD:406560	44/184 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	33..292		89/297 (30%)
		HABP4_PAI-RBP1	189..313	CDD:398441	55/124 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	328..408		33/154 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147231
Domainoid	1	1.000	79	1.000	Domainoid score	I8662
eggNOG	1	0.900	-	-		E1_KOG2945
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	137	1.000	Inparanoid score	I4546
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48663
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002116
OrthoInspector	1	1.000	-	-		mtm8547
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12299
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5307
SonicParanoid	1	1.000	-	-		X1570
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.890