DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment TfIIS and AT5G42325

DIOPT Version :9

Sequence 1:	NP_001260457.1	Gene:	TfIIS / 34883	FlyBaseID:	FBgn0010422	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_680377.1	Gene:	AT5G42325 / 834238	AraportID:	AT5G42325	Length:	233	Species:	Arabidopsis thaliana

Alignment Length:	276	Identity:	51/276 - (18%)
Similarity:	99/276 - (35%)	Gaps:	89/276 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 EVFRIQKKMSKMASDGTGQDQALDLLKALQTL-----NINLDILTKTRIGMTVNELRKSSKDDEV 65
            |:|....:.:|.........:.|..:.|:..|     ::..|::.||.:|..:. .....|:.::
plant     8 ELFEAALRAAKSVKGAESSPEVLRFVDAMNRLKEAPKSLVCDVVCKTSMGKGLG-FFIDHKNPKI 71

  Fly    66 IALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSASKSTSAAKSSSSISGKDKSSSSSSSKD 130
            .:..:.|...|.:.                                  ...||::|      |:|
plant    72 RSEGRILRDLWMKI----------------------------------HYASGREK------SRD 96

  Fly   131 KEKKGSTSSSQTSFPSGGMTDAVRIKCREMLATALKIGEVPEGCGEPEEMAAELEDAIYSEFNNT 195
            :|......:..|...:|   |:.|.|..|:|.::|            .::|.|:.|        |
plant    97 RETPVKIPTHSTMKKTG---DSKRDKVHEILQSSL------------AKVATEVVD--------T 138

  Fly   196 DMKYK--------------NRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMK 246
            :||.:              ....|.:.|:.|..||.||...:.|.::.::|.||..:||.|::::
plant   139 EMKRRVMTVCDPWVVAVSVESAMSILFNMGDSNNPDLRRKVLIGEISGERLVKMEKDEMGSEKIQ 203

  Fly   247 ------KLREKFVKEA 256
                  |.|.:|.:|:
plant   204 KEVQRIKERARFKEES 219

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_001260457.1	TFSII	5..313	CDD:273592	51/276 (18%)
		TFS2N	7..82	CDD:197766	12/79 (15%)
		TFIIS_M	151..257	CDD:284835	30/126 (24%)
		Zn-ribbon_TFIIS	266..312	CDD:259796
AT5G42325	NP_680377.1	TFIIS_I	11..85	CDD:238107	11/74 (15%)
AT5G42325	NP_680377.1	TFIIS_M	118..208	CDD:295406	24/109 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579101at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820