Protein Alignment TfIIS and TCEA3

DIOPT Version :10

• Sequence 1: NP_476967.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: XP_016857689.1
• Gene: TCEA3 / 6920
• HGNCID: 11615
• Length: 487
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 160/347 - (46%)
• Similarity: 213/347 - (61%)
• Gaps: 37/347 - (10%)

  Fly     1 MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEV 65
            |..|||:.||.||:.||.: ....:.||||||.|.:..:::.:|..||||:.||.:||...|.||
Human     1 MGQEEELLRIAKKLEKMVA-RKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCSDKEV 64

  Fly    66 IALAKTLIKNWKRFLASPAPTTPNNSSAKEGSS------------------------NNSSASKS 106
            ::|||.|||||||.|.||.|........:|.:.                        .:....:.
Human    65 VSLAKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTRRD 129

  Fly   107 TSAAKSSSSISGKDKS---SSSSSSKDKEKKGSTSSSQTSFPSGGMT--------DAVRIKCREM 160
            :..:|||:|.|.|..|   |:||.||.:..|..:|....:|.|....        |:||.||.||
Human   130 SVDSKSSASSSPKRPSVERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPCYLTGDSVRDKCVEM 194

  Fly   161 LATALKIGEVPEGCG-EPEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMC 224
            |:.|||..:..:..| ..::||:|:||.||.|..:|||||:||:|||::|||||:|||||.|.:.
Human   195 LSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLS 259

  Fly   225 GAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQ 289
            ||::|..:||||.|||||||:::||....:|||.:.|:|...||.|||.:|:||||:||||||:|
Human   260 GAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQ 324

  Fly   290 TRSADEPMTTFVMCNECGNRWK 311
            ||||||||||||:|||||||||
Human   325 TRSADEPMTTFVLCNECGNRWK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_476967.1	TFSII	5..313	CDD:273592	158/343 (46%)
TCEA3	XP_016857689.1	TFSII	5..346	CDD:273592	156/341 (46%)