Protein Alignment TfIIS and TCEA3

DIOPT Version :9

• Sequence 1: NP_001260457.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: XP_016857689.1
• Gene: TCEA3 / 6920
• HGNCID: 11615
• Length: 487
• Species: Homo sapiens
• Alignment Length: 347
• Identity: 160/347 - (46%)
• Similarity: 213/347 - (61%)
• Gaps: 37/347 - (10%)

  Fly     1 MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEV 65
            |..|||:.||.||:.||.: ....:.||||||.|.:..:::.:|..||||:.||.:||...|.||
Human     1 MGQEEELLRIAKKLEKMVA-RKNTEGALDLLKKLHSCQMSIQLLQTTRIGVAVNGVRKHCSDKEV 64

  Fly    66 IALAKTLIKNWKRFLASPAPTTPNNSSAKEGSS------------------------NNSSASKS 106
            ::|||.|||||||.|.||.|........:|.:.                        .:....:.
Human    65 VSLAKVLIKNWKRLLDSPGPPKGEKGEEREKAKKKEKGLECSDWKPEAGLSPPRKKREDPKTRRD 129

  Fly   107 TSAAKSSSSISGKDKS---SSSSSSKDKEKKGSTSSSQTSFPSGGMT--------DAVRIKCREM 160
            :..:|||:|.|.|..|   |:||.||.:..|..:|....:|.|....        |:||.||.||
Human   130 SVDSKSSASSSPKRPSVERSNSSKSKAESPKTPSSPLTPTFASSMCLLAPCYLTGDSVRDKCVEM 194

  Fly   161 LATALKIGEVPEGCG-EPEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMC 224
            |:.|||..:..:..| ..::||:|:||.||.|..:|||||:||:|||::|||||:|||||.|.:.
Human   195 LSAALKADDDYKDYGVNCDKMASEIEDHIYQELKSTDMKYRNRVRSRISNLKDPRNPGLRRNVLS 259

  Fly   225 GAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQ 289
            ||::|..:||||.|||||||:::||....:|||.:.|:|...||.|||.:|:||||:||||||:|
Human   260 GAISAGLIAKMTAEEMASDELRELRNAMTQEAIREHQMAKTGGTTTDLFQCSKCKKKNCTYNQVQ 324

  Fly   290 TRSADEPMTTFVMCNECGNRWK 311
            ||||||||||||:|||||||||
Human   325 TRSADEPMTTFVLCNECGNRWK 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_001260457.1	TFSII	5..313	CDD:273592	158/343 (46%)
		TFS2N	7..82	CDD:197766	36/74 (49%)
		TFIIS_M	151..257	CDD:284835	58/106 (55%)
		Zn-ribbon_TFIIS	266..312	CDD:259796	38/46 (83%)
TCEA3	XP_016857689.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5307
eggNOG	1	0.900	-	-		E1_COG1594
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H20684
Inparanoid	1	1.050	300	1.000	Inparanoid score	I2700
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579101at2759
OrthoFinder	1	1.000	-	-		FOG0001112
OrthoInspector	1	1.000	-	-		otm41267
orthoMCL	1	0.900	-	-		OOG6_101177
Panther	1	1.100	-	-	O	PTHR11477
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2312
SonicParanoid	1	1.000	-	-		X770
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.860