Protein Alignment TfIIS and TCEA2

DIOPT Version :10

• Sequence 1: NP_476967.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: XP_005260286.1
• Gene: TCEA2 / 6919
• HGNCID: 11614
• Length: 324
• Species: Homo sapiens
• Alignment Length: 316
• Identity: 147/316 - (46%)
• Similarity: 208/316 - (65%)
• Gaps: 25/316 - (7%)

  Fly     1 MSVEEEVFRIQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEV 65
            |..|||:.||.:::.||.:..:.:. |:|||:.|:.:.|.|.:|..||:||:||.|||.|.|:||
Human     2 MGKEEEIARIARRLDKMVTKKSAEG-AMDLLRELKAMPITLHLLQSTRVGMSVNALRKQSSDEEV 65

  Fly    66 IALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSASKSTSAAKSSS-SISGKDKSSSSSSSK 129
            |||||:|||:||:.|                   ::|.:|:....:... ..|.:|.|.:...|:
Human    66 IALAKSLIKSWKKLL-------------------DASDAKARERGRGMPLPTSSRDASEAPDPSR 111

  Fly   130 DKEK--KGSTSSSQTSFPSGGMT-DAVRIKCREMLATALKIGEVPEGCG-EPEEMAAELEDAIYS 190
            .:.:  :..::...|:||...:| ||||.||||||..||:........| :.|.::|::|:.|:.
Human   112 KRPELPRAPSTPRITTFPPVPVTCDAVRNKCREMLTAALQTDHDHVAIGADCERLSAQIEECIFR 176

  Fly   191 EFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKE 255
            :..|||||||||:|||::||||.|||.||.|.:|||:|.:|:|.||.|||||||:|::|:...||
Human   177 DVGNTDMKYKNRVRSRISNLKDAKNPDLRRNVLCGAITPQQIAVMTSEEMASDELKEIRKAMTKE 241

  Fly   256 AINDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWK 311
            ||.:.|:|...||:|||..|.||:|:||||.|:||||:||||||||:|||||||||
Human   242 AIREHQMARTGGTQTDLFTCGKCRKKNCTYTQVQTRSSDEPMTTFVVCNECGNRWK 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_476967.1	TFSII	5..313	CDD:273592	145/312 (46%)
TCEA2	XP_005260286.1	TFSII	6..297	CDD:273592	143/310 (46%)