Protein Alignment TfIIS and TCEA1

DIOPT Version :10

• Sequence 1: NP_476967.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_006747.1
• Gene: TCEA1 / 6917
• HGNCID: 11612
• Length: 301
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 158/317 - (49%)
• Similarity: 213/317 - (67%)
• Gaps: 22/317 - (6%)

  Fly     3 VEEEVFRIQKKMSKMA--SDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEV 65
            :|:||.|..|||.||.  .:..|   ||||||.|:.:.:.|::|..|||||:||.:||.|.|:||
Human     1 MEDEVVRFAKKMDKMVQKKNAAG---ALDLLKELKNIPMTLELLQSTRIGMSVNAIRKQSTDEEV 62

  Fly    66 IALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSASKSTSAAKSSSSISGKDKSSSSSS-SK 129
            .:|||:|||:||:.|..|:            :..:....|...|..|.:|...:::|:||.: |.
Human    63 TSLAKSLIKSWKKLLDGPS------------TEKDLDEKKKEPAITSQNSPEAREESTSSGNVSN 115

  Fly   130 DKEKKGSTSSSQTSFPSGGMT-DAVRIKCREMLATALKIGE--VPEGCGEPEEMAAELEDAIYSE 191
            .|::..:..:..:|||....| |:||:|||||||.||:.|:  :..|..| ||:.:::|:|||.|
Human   116 RKDETNARDTYVSSFPRAPSTSDSVRLKCREMLAAALRTGDDYIAIGADE-EELGSQIEEAIYQE 179

  Fly   192 FNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEA 256
            ..|||||||||:|||::||||.|||.||.|.:||.:.....|:||.|||||||:|::|:...|||
Human   180 IRNTDMKYKNRVRSRISNLKDAKNPNLRKNVLCGNIPPDLFARMTAEEMASDELKEMRKNLTKEA 244

  Fly   257 INDAQLATVQGTKTDLLKCAKCKKRNCTYNQLQTRSADEPMTTFVMCNECGNRWKFC 313
            |.:.|:|...||:|||..|.||||:||||.|:|||||||||||||:|||||||||||
Human   245 IREHQMAKTGGTQTDLFTCGKCKKKNCTYTQVQTRSADEPMTTFVVCNECGNRWKFC 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_476967.1	TFSII	5..313	CDD:273592	155/313 (50%)
TCEA1	NP_006747.1	TFSII	4..301	CDD:273592	155/312 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	80..137		13/68 (19%)