DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment TfIIS and CG8117

DIOPT Version :9

Sequence 1:	NP_001260457.1	Gene:	TfIIS / 34883	FlyBaseID:	FBgn0010422	Length:	313	Species:	Drosophila melanogaster
Sequence 2:	NP_573049.2	Gene:	CG8117 / 32499	FlyBaseID:	FBgn0030663	Length:	162	Species:	Drosophila melanogaster

Alignment Length:	163	Identity:	104/163 - (63%)
Similarity:	134/163 - (82%)	Gaps:	2/163 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly   149 MTDAVRIKCREMLATALKIGEVPEGCGEPEEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDP 213
            |:..:|||||||||||||.|.:|.|||:|::|||:||||||.:.|...:|||||||||:|||:||
  Fly     1 MSMEIRIKCREMLATALKSGNMPPGCGDPDDMAAKLEDAIYGDLNGCKVKYKNRIRSRLANLRDP 65

  Fly   214 KNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREKFVKEAINDAQLATVQGTKTDLLKCAKC 278
            |||.||..|:.|.:|.::|:||||||||||:||::|:|:|:::||.||:|.|||||||..||.:|
  Fly    66 KNPELRQKFLLGQITPEELSKMTPEEMASDDMKQMRQKYVQDSINAAQMAKVQGTKTDQFKCERC 130

  Fly   279 KKRNCTYNQLQTRSADEPMTTFVMCNECGNRWK 311
            .||||  :||..|..|||:.|||:|:|||||||
  Fly   131 DKRNC--SQLHIRDGDEPIITFVICDECGNRWK 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_001260457.1	TFSII	5..313	CDD:273592	104/163 (64%)
		TFS2N	7..82	CDD:197766
		TFIIS_M	151..257	CDD:284835	67/105 (64%)
		Zn-ribbon_TFIIS	266..312	CDD:259796	30/46 (65%)
CG8117	NP_573049.2	TFIIS_M	3..109	CDD:284835	67/105 (64%)
CG8117	NP_573049.2	Zn-ribbon	118..161	CDD:295390	28/44 (64%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45472679
Domainoid	1	1.000	70	1.000	Domainoid score	I3395
eggNOG	1	0.900	-	-		E1_COG1594
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	135	1.000	Inparanoid score	I1834
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1579101at2759
OrthoFinder	1	1.000	-	-		FOG0001112
OrthoInspector	1	1.000	-	-		mtm1141
orthoMCL	1	0.900	-	-		OOG6_101177
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2312
SonicParanoid	1	1.000	-	-		X770
	11	10.730