Protein Alignment TfIIS and TCEANC

DIOPT Version :10

• Sequence 1: NP_476967.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: NP_689847.2
• Gene: TCEANC / 170082
• HGNCID: 28277
• Length: 381
• Species: Homo sapiens
• Alignment Length: 340
• Identity: 97/340 - (28%)
• Similarity: 161/340 - (47%)
• Gaps: 49/340 - (14%)

  Fly    10 IQKKMSKMASDGTGQDQALDLLKALQTLNINLDILTKTRIGMTVNELRKSSKDDEVIALAKTLIK 74
            |::.|||...:..|..     |..|:|:.:..:.|.:|.:...|..:.|:.....:...||.|:.
Human    44 IEQLMSKRNFEDLGNH-----LTELETIYVTKEHLQETDVVRAVYRVLKNCPSVALKKKAKCLLS 103

  Fly    75 NWK---RFLASPAPTTP------NNSSAKEGSSNNSSASKSTSAAKSSSSISGKDKSSSSS---- 126
            .||   :...|.|..:|      .|.....|.|::.|.:: |....||:|:|.:|.:..|.
Human   104 KWKAVYKQTHSKARNSPKLFPVRGNKEENSGPSHDPSQNE-TLGICSSNSLSSQDVAKLSEMIVP 167

  Fly   127 -----SSKDKEKK-GSTSSSQTSFPSGGMTD---AVRIKCREMLATALKIGEVPEGCGEP----- 177
                 ..|.||:. |......|...|..:.|   .:|.||.|:|..||    ......:|
Human   168 ENRAIQLKPKEEHFGDGDPESTGKRSSELLDPTTPMRTKCIELLYAAL----TSSSTDQPKADLW 228

  Fly   178 EEMAAELEDAIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMAS 242
            :..|.|:|:.:::.::....|||..|||:|||||:|:|..|:.|.:.|..:.::.|:||..|||:
Human   229 QNFAREIEEHVFTLYSKNIKKYKTCIRSKVANLKNPRNSHLQQNLLSGTTSPREFAEMTVMEMAN 293

  Fly   243 DEMKKLREKFVKEAINDAQL-ATVQGTKTDLLKCAKCKKRNCTY-----------NQLQTRSADE 295
            .|:|:||..:.:..|.:..| ..:.||:|:.:||.:|:|.||..           :.::..:.||
Human   294 KELKQLRASYTESCIQEHYLPQVIDGTQTNKIKCRRCEKYNCKVTVIDRGTLFLPSWVRNSNPDE 358

  Fly   296 PMTTFVMCNECGNRW 310
            .|.|:|:|||||.:|
Human   359 QMMTYVICNECGEQW 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_476967.1	TFSII	5..313	CDD:273592	97/340 (29%)
TCEANC	NP_689847.2	TFSII	36..373	CDD:273592	96/338 (28%)
		TFIIS_M	202..311	CDD:462184	38/112 (34%)