Protein Alignment TfIIS and DIDO1

DIOPT Version :9

• Sequence 1: NP_001260457.1
• Gene: TfIIS / 34883
• FlyBaseID: FBgn0010422
• Length: 313
• Species: Drosophila melanogaster
• Sequence 2: XP_011526806.1
• Gene: DIDO1 / 11083
• HGNCID: 2680
• Length: 2276
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 58/260 - (22%)
• Similarity: 101/260 - (38%)
• Gaps: 77/260 - (29%)

  Fly    56 LRKSSKDDE-------VIALAKTLIKNWKRFLASPAPTTPNNSSAKEGSSNNSSAS--------- 104
            |.||:|:|.       .:|.:|............||   |.|...|:.|..|.:|:
Human   563 LYKSTKEDRRSEEKAAAMAASKKTAPPGSAVGKQPA---PRNLVPKKSSFANVAAATPAIKKPPS 624

  Fly   105 --KST-------SAAKSSSSISGKDKSSSSSSSKDKEKK--GSTS-------------------- 138
              |.|       ||..||.:.:.:....:.:::....||  ||.:
Human   625 GFKGTIPKRPWLSATPSSGASAARQAGPAPAAATAASKKFPGSAALVGAVRKPVVPSVPMASPAP 689

  Fly   139 ------SSQTSFPSGGMTDAVRIKCREML-----------ATALKIGEVPEGCGEPEEMAAELED 186
                  |:..|.|:..:...:|...:|:|           .|..::|::          |..:|.
Human   690 GRLGAMSAAPSQPNSQIRQNIRRSLKEILWKRVNDSDDLIMTENEVGKI----------ALHIEK 744

  Fly   187 AIYSEFNNTDMKYKNRIRSRVANLKDPKNPGLRGNFMCGAVTAKQLAKMTPEEMASDEMKKLREK 251
            .:::.|..||.:||::.||.:.|||||||.||....:...::..:|.::.|||:.|.|:...:|:
Human   745 EMFNLFQVTDNRYKSKYRSIMFNLKDPKNQGLFHRVLREEISLAKLVRLKPEELVSKELSTWKER 809

  Fly   252  251
            Human   810  809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TfIIS	NP_001260457.1	TFSII	5..313	CDD:273592	58/260 (22%)
		TFS2N	7..82	CDD:197766	7/32 (22%)
		TFIIS_M	151..257	CDD:284835	30/112 (27%)
		Zn-ribbon_TFIIS	266..312	CDD:259796
DIDO1	XP_011526806.1	TNG2	<160..302	CDD:227367
		PHD_DIDO1_like	266..319	CDD:277109
		TFS2M	708..809	CDD:128786	29/110 (26%)
		SPOC	1093..1199	CDD:285043

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910