Protein Alignment ck and MYA1

DIOPT Version :10

• Sequence 1: NP_523571.1
• Gene: ck / 34882
• FlyBaseID: FBgn0000317
• Length: 2167
• Species: Drosophila melanogaster
• Sequence 2: NP_173201.2
• Gene: MYA1 / 838333
• AraportID: AT1G17580
• Length: 1520
• Species: Arabidopsis thaliana
• Alignment Length: 1499
• Identity: 469/1499 - (31%)
• Similarity: 720/1499 - (48%)
• Gaps: 219/1499 - (14%)

  Fly     3 IVTRGDYIWIEPASGREFDVAIGARVVSAEGRRIQVRDDDGDEVWLAPERRIKAMHASSVQGVED 67
            ::..|.::|:|.......|    ..|...:|..:.|:...|..| :......|...|.| .||:|
plant     5 VIIVGSHVWVEDPHLAWID----GEVTRIDGINVHVKTKKGKTV-VTNVYFPKDTEAPS-GGVDD 63

  Fly    68 MISLGDLHEAGILRNLLIRYKENLIYTYTGSILVAVNPYQILP-IYTGDQIKLYKERKIGELPPH 131
            |..|..|||.|:||||..||:.|.||||||:||:||||:|.|| ||..|.::.||...:|||.||
plant    64 MTKLSYLHEPGVLRNLETRYELNEIYTYTGNILIAVNPFQRLPHIYETDMMEQYKGIALGELSPH 128

  Fly   132 IFAIGDNAYAHMKRYRQDQCIVISGESGAGKTESTKLILQYLAAISGKHS----WIEQQILEANP 192
            :|||||.||..|....::..|::||||||||||:||::::|||.:.|:..    .:|||:||:||
plant   129 VFAIGDAAYRAMINEGKNNSILVSGESGAGKTETTKMLMRYLAFLGGRSGVEGRTVEQQVLESNP 193

  Fly   193 ILEAFGNAKTIRNDNSSRFGKYIDIHFSANGVIEGAKIEQYLLEKSRIVSQNHSERNYHVFYCIL 257
            :|||||||||:||:|||||||:::|.|..||.|.||.|..||||:||:...:..|||||.||.:.
plant   194 VLEAFGNAKTLRNNNSSRFGKFVEIQFDKNGRISGAAIRTYLLERSRVCQISDPERNYHCFYLLC 258

  Fly   258 AGLSADEKSRLDLGMAADYKYLTGGNSITCEGRDDAAEFSDIRSAMKVLLFSDQEIWEIIKLLAA 322
            |....|.| :..|.....:.||...:....:|.|||:|:.:.|.||.|:..|::|...|.:::||
plant   259 AAPPEDIK-KYKLENPHKFHYLNQSSCYKLDGVDDASEYLETRRAMDVVGISNEEQEAIFRVVAA 322

  Fly   323 LLHCGNIKY------KATVVDNLDATEIPEHINVERVAGLLGLPIQPLIDALTRRTLFAHGETVV 381
            :||.|||.:      .::|:.:.|:.   .|:|:  .|.||....|.|.|||.||.:....|.:.
plant   323 ILHLGNIDFGKGEEIDSSVIKDKDSR---SHLNM--AAELLMCNAQSLEDALIRRVMVTPEEIIT 382

  Fly   382 STLSRDQSVDVRDAFVKGIYGRMFVHIVRKINTAIFK-PRGTSRNAIGVLDIFGFENFDQNSFEQ 445
            .||..|.::..||...|.||..:|..||.||||:|.: ||  |::.||||||:|||:|..|||||
plant   383 RTLDPDNAIASRDTLAKTIYSHLFDWIVNKINTSIGQDPR--SKSIIGVLDIYGFESFKCNSFEQ 445

  Fly   446 FCINYANENLQQFFVQHIFKLEQEEYNHEAINWQHIEFVDNQDALDLIAIKQLNIMALIDEEARF 510
            ||||:.||.|||.|.||:||:|||||..|.|.|.:|||:||||.|:||..|...|::|:||...|
plant   446 FCINFTNEKLQQHFNQHVFKMEQEEYTKEEIAWSYIEFIDNQDVLELIEKKPGGIISLLDEACMF 510

  Fly   511 PKGTDQTMLAKLHKTHGSHKNYLKPKSDINTSFGLNHFAGVVFYDTRGFLDKNRDTFSPDLLHLV 575
            ||.|.:|...||.:|...|:.:.|||.. .|.|.::|:||.|.|.:..|:|||:|....:...|.
plant   511 PKSTHETFSQKLFQTFKEHERFAKPKLS-RTDFTISHYAGEVTYQSNHFIDKNKDYIVAEHQALF 574

  Fly   576 SQSTNKFLRQIFAQDIEMGAETRKRTPTLSTQFRKSLDALMKTLSSCQPFFIRCIKPNELKKPMM 640
            :.|..||:..:|....|..:.:.|.: ::.::|::.|.:||::|:..:|.:|||||||.:.||.:
plant   575 TASNCKFVAGLFHALHEDSSRSSKFS-SIGSRFKQQLHSLMESLNGTEPHYIRCIKPNNVLKPGI 638

  Fly   641 FDRGLCCRQLRYSGMMETIRIRRAGYPIRHGFREFVERYRFLIPGVPPAHRTDCQAATSRICAVV 705
            |:......|||..|::|.|||..||||.|..|.:|::|:..|.|.|...:..|..|     |.::
plant   639 FENFNVIHQLRCGGVLEAIRISCAGYPTRLAFYDFLDRFGLLAPEVLEGNYDDKVA-----CQMI 698

  Fly   706 LGK---SDYQLGHTKVFLKDAHDLFLEQERDRVLTRKILILQRSIRGWVYRRRF----------- 756
            |.|   :|||:|.||:||:......|:..|..||.....::||..|..:.|:.:
plant   699 LDKKSLTDYQIGKTKIFLRAGQMAELDARRAEVLGNAARVIQRQFRTCMARKNYRSIRNAAIVLQ 763

  Fly   757 --------------LRLRAAAITVQRFWKGYAQRKRYRNMRVGYMRLQALIRSRVL--SHRFRHL 805
                          ||:.|||:.||:.::.|..||.:...|...:.||..:|:.:.  ..|.|..
plant   764 SFLRGEIARAVHKKLRIEAAALRVQKNFRRYVDRKSFVTTRSSTIVLQTGLRAMIARSEFRLRRQ 828

  Fly   806 RGHIVGLQAHARGYLVRREYGHKMWAVIKIQSHVRRMIAMRRYRKLRLEHKQFAEVLQLR-KLEE 869
            |...:.||||.||......|.....|.|..|...|..:|.|..|.|::..:....:...: |||:
plant   829 RKAAIVLQAHWRGRQAFSYYTRLQKAAIVTQCAWRCRLARRELRMLKMAARDTGALKDAKNKLEQ 893

  Fly   870 --QEL---LHRGNKHAREIAEQHYRDRLHELERREI---QEQLENRR------------RVEVNM 914
              :||   ||         .|:..|..|.|.:.:|:   ||.|...|            ..|...
plant   894 RVEELSLRLH---------LEKRLRTDLEEAKVQEVAKLQEALHTMRLQLKETTAMVVKEQEAAR 949

  Fly   915 NIINDAARKQEEP--VDDGKLVEAMFDFLPDSSSDAPTPHG--GRETSVFNDLPHAQN---VNQD 972
            ..|.:|:...:||  |:|.:.::::       |::.....|  ..||...::..||..   |..:
plant   950 VAIEEASSVNKEPVVVEDTEKIDSL-------SNEIDRLKGLLSSETHKADEAQHAYQSALVQNE 1007

  Fly   973 DIIAPIHISEDEEDLSEFKFQKFAATYFQGNVNHQYAKKALKHPLLPLHTQGDQLAAQALWITIL 1037
            ::...:..:..:.|..:...|:|....|    :.:...|.|:...|.:......||.:.. .||:
plant  1008 ELCKKLEEAGRKIDQLQDSVQRFQEKVF----SLESENKVLRQQTLTISPTTRALALRPK-TTII 1067

  Fly  1038 RFTGDMPEPKYHTMDRMDTTSVMSKVTATLGRNFIRSK--EFQEAQLMGLDPD-AFLKQKP---- 1095
            :.|     |:..|....:||.:....|....:..:..|  |.||..|..:..| .|.:.||
plant  1068 QRT-----PEKDTFSNGETTQLQEPETEDRPQKSLNQKQQENQELLLKSISEDIGFSEGKPVAAC 1127

  Fly  1096 ---------RSIRHKLVSLTLKRKNKLGEDVRRRLQDDEYTADSYQSWLQSRPTSNLEKLHFIIG 1151
                     ||...:..|:.    |::.|.:...::..| .:|....||.:..|. |..|...:.
plant  1128 LIYKCLIHWRSFEVERTSIF----NRIIETIASAIEMQE-NSDVLCYWLSNSATL-LMFLQRTLK 1186

  Fly  1152 HGIL-------RAELRDEIYCQICK------QLTNNPLKSSHARGWILLSL-CVGCFAPSEKFVN 1202
            .|..       |..:...::.::.:      |....|..:..|.|..|..| .|....|:..|..
plant  1187 AGATGSITTPRRRGMPSSLFGRVSQSFRGSPQSAGFPFMTGRAIGGGLDELRQVEAKYPALLFKQ 1251

  Fly  1203 YLRAFI------------REGPPGYAPYC------------EERLKRTFNNGTRNQP--PSWLEL 1241
            .|.||:            :|..|..|. |            :.|.:.|.||....:|  ..|..:
plant  1252 QLTAFLEKIYGMIRDKMKKEISPLLAS-CIQVPRTPRSGLVKGRSQNTQNNVVAPKPMIAHWQNI 1315

  Fly  1242 QATKSKKPIMLPITFMDGNTKTLLADSATTARELCNQLSDKISLKDQFGFSLYIALFDKV----- 1301
                        :|.::|:.:|:.|:...:.  |.:::..:|     |.| :.:.||:.:
plant  1316 ------------VTCLNGHLRTMRANYVPSL--LISKVFGQI-----FSF-INVQLFNSLLLRRE 1360

  Fly  1302 SSLGSGGDHVMDAISQCEQYAKEQGAQERNAPWRLFFRKEIFAPWHEPTHDQVATN--LIYQQVV 1364
            ....|.|::|...:::.|::..:  |.|          :.:.:.|.|..|.:.|..  :|:|:..
plant  1361 CCSFSNGEYVKTGLAELEKWCHD--ATE----------EFVGSAWDELKHIRQAVGFLVIHQKPK 1413

  Fly  1365 RGVK 1368
            :.:|
plant  1414 KSLK 1417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ck	NP_523571.1	MYSc_Myo7	77..721	CDD:276832	293/658 (45%)
		MyTH4	<1138..1245	CDD:214535	27/146 (18%)
		FERM1_F1_Myosin-VII	1249..1347	CDD:340612	16/102 (16%)
		B41	1251..1467	CDD:214604	23/125 (18%)
		FERM_C1_MyoVII	1461..1559	CDD:270019
		SH3	1560..1624	CDD:473055
		MyTH4	1701..1849	CDD:214535
		FERM2_F1_Myosin-VII	1854..1951	CDD:340613
		B41	1856..2068	CDD:214604
		FERM_C2_MyoVII	2064..2159	CDD:270020
MYA1	NP_173201.2	Myosin_N	8..47	CDD:460670	9/43 (21%)
		MYSc_Myo11	73..717	CDD:276835	293/658 (45%)
		sbcc	<718..>1117	CDD:129705	93/424 (22%)
		COG1340	<868..1047	CDD:440951	39/198 (20%)
		MyosinXI_CBD	1099..1486	CDD:271259	68/358 (19%)