Protein Alignment ck and Myo1d

DIOPT Version :9

• Sequence 1: NP_001285949.1
• Gene: ck / 34882
• FlyBaseID: FBgn0000317
• Length: 2167
• Species: Drosophila melanogaster
• Sequence 2: XP_036012676.1
• Gene: Myo1d / 338367
• MGIID: 107728
• Length: 1010
• Species: Mus musculus
• Alignment Length: 1116
• Identity: 360/1116 - (32%)
• Similarity: 546/1116 - (48%)
• Gaps: 205/1116 - (18%)

  Fly    47 WLAPERRIKAMHASSVQGVE----DMISLGDLHEAGILRNLLIRYKENLIYTYTGSILVAVNPYQ 107
            |:..:|  ..:|.|:|:.||    ..:::...|        :.|:::..|||:.|.::|:||||:
Mouse     3 WINQQR--NTLHWSTVRRVEGKTQSCLTVELKH--------MCRFEKGRIYTFIGEVVVSVNPYK 57

  Fly   108 ILPIYTGDQIKLYKERKIGELPPHIFAIGDNAYAHMKRYRQDQCIVISGESGAGKTESTKLILQY 172
            :|.||..|.::.||.|::.|.|||:|||.|.||..|||..:|.||:|||||||||||::|.|:||
Mouse    58 VLNIYGRDTVEQYKGRELYERPPHLFAIADAAYKAMKRRSKDTCIMISGESGAGKTEASKYIMQY 122

  Fly   173 LAAIS--GKHSWIEQ---QILEANPILEAFGNAKTIRNDNSSRFGKYIDIHFSANGVIEGAKIEQ 232
            :|||:  .:.:.||:   .:|::|.:|||||||||.|||||||||||:||:|...|...|..|..
Mouse   123 IAAITNPSQRAEIERVKNMLLKSNCVLEAFGNAKTNRNDNSSRFGKYMDINFDFKGDPIGGHINN 187

  Fly   233 YLLEKSRIVSQNHSERNYHVFYCILAGLSADEKSRLDLGMA-ADYKYLTGGNSITCEGRDDAAEF 296
            |||||||::.|...||::|.||.:|.|.|......|.|..: :.|.|:..|..:. ...:|||||
Mouse   188 YLLEKSRVIVQQPGERSFHSFYQLLQGGSEQMLHSLHLQKSLSSYNYIRVGAQLK-SSINDAAEF 251

  Fly   297 SDIRSAMKVLLFSDQEIWEIIKLLAALLHCGNIKYKATVVDNLDATEIPEHINVERVAGLLGLPI 361
            ..:..||||:.|..:||..:.|:||.:||.||:|:   :||. |...|.....|..:|.||....
Mouse   252 KVVADAMKVIGFKPEEIQTVYKILAVILHLGNLKF---IVDG-DTPLIENGKVVSVIAELLSTKA 312

  Fly   362 QPLIDALTRRTLFAHGETVVSTLSRDQSVDV-RDAFVKGIYGRMFVHIVRKINTAI-FKPRGTS- 423
            ..:..||..||: |.|..::.....:|.... ||||.|.||.|:|..||.:||..| .|...|:
Mouse   313 DMVEKALLYRTV-ATGRDIIDKQHTEQEASYGRDAFAKAIYERLFCWIVTRINDIIEVKNYDTTI 376

  Fly   424 ---RNAIGVLDIFGFENFDQNSFEQFCINYANENLQQFFVQHIFKLEQEEYNHEAINWQHIEFVD 485
               ...||||||:|||.||.||||||||||.||.|||.|:|.:.|.|||||..|.|.|:||::.:
Mouse   377 HGKNTVIGVLDIYGFEIFDNNSFEQFCINYCNEKLQQLFIQLVLKQEQEEYQREGIPWKHIDYFN 441

  Fly   486 NQDALDLIAIKQLNIMALIDEEA-RFPKGTDQTMLAKLHKTHGSHKNYLKPKS-------DINTS 542
            ||..:||:..:...|:|::|:.. ...|.||...|..|:...|.|.::...|:       :.:..
Mouse   442 NQIIVDLVEQQHKGIIAILDDACMNVGKVTDGMFLEALNSKLGKHGHFSSRKTCASDKILEFDRD 506

  Fly   543 FGLNHFAGVVFYDTRGFLDKNRDTFSPDLLHLVSQSTNKFLRQIFAQDIEMGAETRKRTPTLSTQ 607
            |.:.|:||.|.|...||:|||:||...|...|:..|:|..|:.::.:......|..||..|.:|.
Mouse   507 FRIRHYAGDVVYSAIGFIDKNKDTLFQDFKRLMYNSSNPVLKNMWPEGKLSITEVTKRPLTAATL 571

  Fly   608 FRKSLDALMKTLSSCQPFFIRCIKPNELKKPMMFDRGLCCRQLRYSGMMETIRIRRAGYPIRHGF 672
            |:.|:.||:..|:|.:|:::||||||:.|.|.:||...|..|:.|.|::|.:|:||||:..|..:
Mouse   572 FKNSMIALVDNLASKEPYYVRCIKPNDKKSPQIFDDERCRHQVEYLGLLENVRVRRAGFAFRQTY 636

  Fly   673 REFVERYRFLIPGVPPAH--RTDCQAATSRI--CAVVLGKSDYQLGHTKVFLKDAHDLF-LEQER 732
            .:|:.||:.:.....|.|  .:|.:|....|  |..   :.|...|.:|:|::....|| ||:.|
Mouse   637 EKFLHRYKMISEFTWPNHDLPSDKEAVKKLIERCGF---QDDVAYGKSKIFIRTPRTLFTLEELR 698

  Fly   733 DRVLTRKILILQRSIRGWVYRRRFLRLRAAAITVQRFWKGYAQRKRYRNMRVGYMRLQALIRSRV 797
            .::|.|.:|.||:..||.:.|.|:.|.: ||:|:.|::      :||:            ::|.:
Mouse   699 AQMLVRVVLFLQKVWRGTLARMRYKRTK-AALTIIRYY------RRYK------------VKSYI 744

  Fly   798 LSHRFRHLRGHIVGLQAHARGYLVRREYG-HKMWAV-IKIQSHVRRMIAMRRYRKLRLEHKQFAE 860
                      |.|..:.|  |....|:|| |..|.. .|:
Mouse   745 ----------HEVARRFH--GVKNMRDYGKHVKWPTPPKV------------------------- 772

  Fly   861 VLQLRKLEE--QELLHRGNKHAREIAEQHYRDRLHELERREIQEQLENRRRVEVNMNII---NDA 920
               ||:.||  |.:.:|.  .|.::.:......|.::..:....::...:|.::.:...   |..
Mouse   773 ---LRRFEEALQSIFNRW--RASQLIKTIPASDLPQVRAKVAAMEMLKGQRADLGLQRAWEGNYL 832

  Fly   921 ARKQEEPVDDGKLVEAMFDFLPDSSSDAPTPHGGRETSVFNDLP------------HAQNVNQDD 973
            |.|.:.|...|       .|:|                |.|:|.            |.:.||:..
Mouse   833 ASKPDTPQTSG-------TFVP----------------VANELKRKDKYMNVLFSCHVRKVNRFS 874

  Fly   974 IIAPIHISEDEEDLSEFKFQKFAATYFQGNVNHQYAKKALKHPLLPLH-------TQG-DQLAAQ 1030
            .:         ||.:.|...:.   .::.:...||  |.:|  .:||:       :.| |||..
Mouse   875 KV---------EDRAIFVTDRH---LYKMDPTKQY--KVMK--TIPLYNLTGLSVSNGKDQLVV- 922

  Fly  1031 ALWITILRFTGDMPEPKYHTMDRMDTTSVMSKVTATLGRNFIRSKEFQEAQLMGLDPDAFLKQKP 1095
                             :||.|..|....:.....|        .|.:..:|:|:..:.|..:|
Mouse   923 -----------------FHTKDNKDLIVCLFSKQPT--------HESRIGELVGVLVNHFKSEK- 961

  Fly  1096 RSIRHKLVSLT 1106
               ||..|::|
Mouse   962 ---RHLQVNVT 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ck	NP_001285949.1	MYSc	64..733	CDD:214580	278/697 (40%)
		MYSc_Myo7	77..721	CDD:276832	271/667 (41%)
		MyTH4	<1138..1245	CDD:214535
		B41	1251..1467	CDD:214604
		FERM_B-lobe	1355..1439	CDD:271216
		FERM_C1_MyoVII	1461..1559	CDD:270019
		SH3	1560..1624	CDD:302595
		MyTH4	1701..1849	CDD:214535
		B41	1856..2068	CDD:214604
		FERM_M	1966..2068	CDD:278785
		FERM_C2_MyoVII	2064..2159	CDD:270020
Myo1d	XP_036012676.1	MYSc_Myo1	36..686	CDD:276829	271/658 (41%)
		Myosin_TH1	807..1000	CDD:399188	41/232 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910