Protein Alignment ck and Myo1f

DIOPT Version :9

• Sequence 1: NP_001285949.1
• Gene: ck / 34882
• FlyBaseID: FBgn0000317
• Length: 2167
• Species: Drosophila melanogaster
• Sequence 2: NP_001101546.1
• Gene: Myo1f / 314654
• RGDID: 1309750
• Length: 1098
• Species: Rattus norvegicus
• Alignment Length: 1105
• Identity: 345/1105 - (31%)
• Similarity: 529/1105 - (47%)
• Gaps: 209/1105 - (18%)

  Fly    58 HASSVQGVEDMISLGDLHEAGILRNLLIRYKENLIYTYTGSILVAVNPYQILPIYTGDQIKLYKE 122
            |.....||:||:.|..:.|..|:.||..|:.::.|:||.||:|::|||::.:|.:|..:|.||:.
  Rat    12 HNVKQSGVDDMVLLPQITEDAIVSNLRKRFMDDYIFTYIGSVLISVNPFKQMPYFTDREIDLYQG 76

  Fly   123 RKIGELPPHIFAIGDNAYAHMKRYRQDQCIVISGESGAGKTESTKLILQYLAAISG---KHSWIE 184
            ....|.||||:|:.||.|.:|....::||::||||||||||.:.|.|:.|::.:||   |...::
  Rat    77 AAQYENPPHIYALTDNMYRNMLIDCENQCVIISGESGAGKTVAAKYIMGYISKVSGGGDKVQHVK 141

  Fly   185 QQILEANPILEAFGNAKTIRNDNSSRFGKYIDIHFSANGVIEGAKIEQYLLEKSRIVSQNHSERN 249
            ..||::||:|||||||||:||:||||||||.:|.||..|..:|.||..:||||||:|.||.:|||
  Rat   142 DIILQSNPLLEAFGNAKTVRNNNSSRFGKYFEIQFSRGGEPDGGKISNFLLEKSRVVMQNENERN 206

  Fly   250 YHVFYCILAGLSADEKSRLDLGMAADYKYLTGGNSITCEGRDDAAEFSDIRSAMKVLLF--SDQE 312
            :|::|.:|.|.|.:::..|.|.....|.||...::...||.||.::|::..:||:|:..  |.|:
  Rat   207 FHIYYQLLEGASQEQQQNLGLMTPDYYYYLNQSDTYKVEGTDDRSDFNETLNAMQVIGIPTSVQQ 271

  Fly   313 IWEIIKLLAALLHCGNIKY----KATVVDNLDATEIPEHINVERVAGLLGLPIQPLIDALTRRTL 373
            :  :::|:|.:||.|||.:    ....|:::|....|        |.|||:....|.:.||.|.:
  Rat   272 L--VLQLVAGILHLGNISFCEEGNYARVESVDLLAFP--------AYLLGIDSGRLQEKLTSRKM 326

  Fly   374 FA----HGETVVSTLSRDQSVDVRDAFVKGIYGRMFVHIVRKINTAIFKPRGTSRNAIGVLDIFG 434
            .:    ..|::..||:.:|:...|||..||:|.|:|..:|..||.|:.||:  ...:||||||:|
  Rat   327 DSKWGGRSESIDVTLNVEQAAYTRDALAKGLYARLFDFLVEAINRAMQKPQ--EEYSIGVLDIYG 389

  Fly   435 FENFDQNSFEQFCINYANENLQQFFVQHIFKLEQEEYNHEAINWQHIEFVDNQDALDLIAIKQLN 499
            ||.|.:|.|||||||:.||.|||.|::...|.|||||..|.|.|..||:.:|:...|||..| ||
  Rat   390 FEIFQKNGFEQFCINFVNEKLQQIFIELTLKAEQEEYVQEGIRWTPIEYFNNKIVCDLIENK-LN 453

  Fly   500 ---IMALIDEEARFPK----GTDQTMLAKLHKTHGSHKNYLKPKSDINTSFGLNHFAGVVFYDTR 557
               ||:::|:......    |.|||:|.||....|:|:::    :..:..|.::|:||.|.||..
  Rat   454 PPGIMSVLDDVCATMHATGGGADQTLLQKLQAAVGTHEHF----NSWSAGFVIHHYAGKVSYDVS 514

  Fly   558 GFLDKNRDTFSPDLLHLVSQSTNKFLRQIFAQDIEMGAETRKRTPTLSTQFRKSLDALMKTLSSC 622
            ||.::|||....||:.|:..|...|||.:|.:.:::  :.:.|..|..::.:|..:.|:.||..|
  Rat   515 GFCERNRDVLFSDLIELMQSSDQAFLRMLFPEKLDV--DKKGRPSTAGSKIKKQANDLVSTLKKC 577

  Fly   623 QPFFIRCIKPNELKKPMMFDRGLCCRQLRYSGMMETIRIRRAGYPIRHGFREFVERYRFLIPGVP 687
            .|.:||||||||.|:|..::......|:.|.|:.|.||:||||:..|..|.:|::||..|.|...
  Rat   578 TPHYIRCIKPNETKRPRDWEESRVKHQVEYLGLRENIRVRRAGFAYRRQFSKFLQRYAILTPETW 642

  Fly   688 PAHRTD-CQAATSRICAVVLGKSDYQLGHTKVFLKDAHDLFLEQERDRVLTRKILILQRSIRGWV 751
            |..|.| .|.....:.||.:....||:|.||||:|:...|||.:|          :.:|...|:
  Rat   643 PRWRGDERQGVQHLLRAVNMEPDQYQMGSTKVFVKNPESLFLLEE----------MRERKFDGF- 696

  Fly   752 YRRRFLRLRAAAITVQRFWKGYAQRKRYRNMRVGYMRLQALIRSRVLSHRFRHLRGHIVGLQAHA 816
                       |.|:|:.|
  Rat   697 -----------ARTIQKAW---------------------------------------------- 704

  Fly   817 RGYLVRREYGHKMWAVIKIQSHVRRMIAMRRYRKLRLEHKQFAEVLQLRKLEEQELLHRGNKHAR 881
                                   ||.||:|:|.::|.|....             ||::..:...
  Rat   705 -----------------------RRHIAVRKYEEMREEASNI-------------LLNKKERRRN 733

  Fly   882 EIAEQHYRDRLHELERREIQEQLENRRRVEVNMNIINDAARKQE---EPVDDGKLVEAMFDFLPD 943
            .|......|.|...||.|:::.|..|.||:     ..|:..|.:   :|:....::.....::..
  Rat   734 SINRNFVGDYLGLEERPELRQFLAKRERVD-----FADSVTKYDRRFKPIKRDLILTPKCVYVIG 793

  Fly   944 SSSDAPTPHGGRETSVFNDLPHAQ-------NVNQDDIIAPIHISEDE------EDLSEFKFQKF 995
            .......|..|....|.......|       :..|||..    |.::|      |.:.:.:|...
  Rat   794 REKVKKGPEKGLVREVLKKKLEIQALRGVSLSTRQDDFF----ILQEEAADSFLESIFKTEFVSL 854

  Fly   996 AATYFQGNVNHQYAKKALKHPLLPLHTQGDQLAAQAL---W-------ITILRFTGDMPEPKYHT 1050
            ....|:         :|.:.| ||| |..|.|..:..   |       :|..|.|||:...|  .
  Rat   855 LCKRFE---------EAARRP-LPL-TFSDMLQFRVKKEGWGGGSTRNVTFSRGTGDLAVLK--A 906

  Fly  1051 MDRMDTTSV---MSKVTATLGRNFIRSKEFQEAQL--------------MGLDPDAFLKQKPRSI 1098
            ..|..|.|:   :.|.|....:...:.:..:.||.              .|:.|.:.::..|..|
  Rat   907 GSRALTISIGDGLPKSTKPTRKGLAQGRPRRSAQAPTRAAPGPPRGLNRNGVPPSSQVRSLPMEI 971

  Fly  1099  1098
              Rat   972  971

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ck	NP_001285949.1	MYSc	64..733	CDD:214580	277/689 (40%)
		MYSc_Myo7	77..721	CDD:276832	266/664 (40%)
		MyTH4	<1138..1245	CDD:214535
		B41	1251..1467	CDD:214604
		FERM_B-lobe	1355..1439	CDD:271216
		FERM_C1_MyoVII	1461..1559	CDD:270019
		SH3	1560..1624	CDD:302595
		MyTH4	1701..1849	CDD:214535
		B41	1856..2068	CDD:214604
		FERM_M	1966..2068	CDD:278785
		FERM_C2_MyoVII	2064..2159	CDD:270020
Myo1f	NP_001101546.1	MYSc	12..690	CDD:214580	278/706 (39%)
		MYSc_Myo1	31..677	CDD:276829	266/664 (40%)
		Myosin_TH1	717..899	CDD:283635	40/214 (19%)
		SH3_MyoIe_If_like	1045..1097	CDD:212761

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910