DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment GABA-B-R1 and Atp1b4

DIOPT Version :9

Sequence 1:	NP_001246033.1	Gene:	GABA-B-R1 / 34878	FlyBaseID:	FBgn0260446	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_445833.2	Gene:	Atp1b4 / 84396	RGDID:	620994	Length:	356	Species:	Rattus norvegicus

Alignment Length:	136	Identity:	28/136 - (20%)
Similarity:	57/136 - (41%)	Gaps:	27/136 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   706 FAFVALAVIFCCFLSMLLI----FVPKVIEVIRHP----KDKAES-KYNPDSAISKEDEERYQK- 760
            |.:.:||.:...|:.||.:    ::|...|.::.|    :..|.| .:|    .:..:.|.:|:
  Rat   117 FFYASLAAVITLFIYMLFLAISPYMPTFTEQVKPPGVMIRPFAHSLNFN----FNVSEPETWQRY 177

  Fly   761 LVTENEELQRLITQKEEKIRV---LRQRLVERGDA---------KGTELNGATGVASAAVA-TTS 812
            :::.|..||......:|::.:   ..|..::.||.         |.:.|...:|:...... :|.
  Rat   178 VISLNGFLQGYNDSLQEEMNIDCPPGQYFIQDGDEDEDKKACQFKRSFLKNCSGLEDPTFGYSTG 242

  Fly   813 QPASLI 818
            ||..|:
  Rat   243 QPCILL 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R1	NP_001246033.1	PBP1_GABAb_receptor	34..437	CDD:107361
		ANF_receptor	52..415	CDD:279440
		7tm_3	476..730	CDD:278433	7/27 (26%)
Atp1b4	NP_445833.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	32..77
Atp1b4	NP_445833.2	Na_K-ATPase	90..348	CDD:395224	28/136 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900