DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment GABA-B-R1 and CG11703

DIOPT Version :9

Sequence 1:	NP_001246033.1	Gene:	GABA-B-R1 / 34878	FlyBaseID:	FBgn0260446	Length:	841	Species:	Drosophila melanogaster
Sequence 2:	NP_650792.1	Gene:	CG11703 / 42307	FlyBaseID:	FBgn0038690	Length:	353	Species:	Drosophila melanogaster

Alignment Length:	172	Identity:	37/172 - (21%)
Similarity:	63/172 - (36%)	Gaps:	53/172 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   231 FYVVAARRVLCEMYKQQLYGRAHVWFFIGWY--------EDNWYEVNLKA-EGITCTVEQMR--I 284
            ||:|....::|           .|.|::|.:        :..|    ||. .|::....|.|  :
  Fly    58 FYLVLYALIVC-----------IVAFWLGIFMLAIIDPNKPRW----LKGPPGLSMVPNQNRSVL 107

  Fly   285 AAEGHLTTEALMWNQNNQTTISGMTAEEFRHRLNQALIEEGYDINHDRYPEGY-QEAPLAYDAVW 348
            |...|:.:|.        ..|:. ..::|.::||...|:...|.|.|. ..|| .|.|
  Fly   108 AYFTHIMSEV--------NPIAD-RIDDFLNKLNDNAIDFFADFNQDT-TWGYATEKP------- 155

  Fly   349 SVALAFNKTMERLTTGKKSLRDFTY-TDKEIADEIYAAMNST 389
            :|.:..||.:..:..        || |..::..|..|::..|
  Fly   156 TVFIKLNKVIGYVPE--------TYDTPDDLPKEAPASLQDT 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
GABA-B-R1	NP_001246033.1	PBP1_GABAb_receptor	34..437	CDD:107361	37/172 (22%)
		ANF_receptor	52..415	CDD:279440	37/172 (22%)
		7tm_3	476..730	CDD:278433
CG11703	NP_650792.1	Na_K-ATPase	32..267	CDD:298651	37/172 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3927
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900