DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Rnmt and pcm1

DIOPT Version :9

Sequence 1:	NP_523568.2	Gene:	Rnmt / 34877	FlyBaseID:	FBgn0286027	Length:	427	Species:	Drosophila melanogaster
Sequence 2:	NP_001342758.1	Gene:	pcm1 / 2539280	PomBaseID:	SPCC330.10	Length:	360	Species:	Schizosaccharomyces pombe

Alignment Length:	398	Identity:	123/398 - (30%)
Similarity:	182/398 - (45%)	Gaps:	71/398 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 ESEGQAETTSAPNQEPHVSKSPREYY---DEPGGKG------NGSGADDQDEPETEAASGAANTH 83
            |:...|..|:..|:........|:|:   |..|.:|      ||:..|
pombe    16 ENRRYARPTAQMNRVIEQQPRRRDYFQNNDNSGRRGYNRHENNGNAQD----------------- 63

  Fly    84 VVAHHYNELKEAGRKDRQKSKIFFMRNFNNWIKSQLINEYMSQIKQNKRMGDALRVLDMCCGKGG 148
            ||..|||...:.|.|.||.|.|..::.|||||||.||.::.......     .:.||||.|||||
pombe    64 VVRSHYNARPDLGYKKRQFSPIIQLKRFNNWIKSVLIQKFAPHASDY-----PILVLDMGCGKGG 123

  Fly   149 DLLKWEKAAISHLICTDIAEVSVEQCQRRYQDILQRSEKSKFANKFTAEFFACDSTLVRLRERYK 213
            ||:||:||.|...|..|||||||.|.::||:::         ...|.|.|:|.|.....:.|...
pombe   124 DLIKWDKAGIDGYIGIDIAEVSVNQAKKRYREM---------HASFDALFYAGDCFSSSINELLP 179

  Fly   214 DPSLQLNLVSCQFAFHYCFESMAQADCMMRNAAECLKPGGFFIATMPDAYEIIRRLRAAGPDARR 278
            ....:.::||.||..||.|||..:...::.|.::||..||..|.|:|::..|::.::...|..:.
pombe   180 PDQRKFDVVSLQFCMHYAFESEEKVRVLLGNVSKCLPRGGVMIGTIPNSDVIVKHIKMLKPGEKE 244

  Fly   279 FGNDVYSIEFDCETDP---LPLFGAKYQFHLE-GVVDCPEFLVHFPTLVKLGRKYGLQLLKRSTF 339
            :|||:|.:.|. |:.|   .|.:|.:|.|:|| .|.|.||::|.|.....:...|.|:|:....|
pombe   245 WGNDIYKVRFP-ESPPRSFRPPYGIQYYFYLEDAVTDVPEYVVPFEAFRAVAEGYNLELIWVKPF 308

  Fly   340 ADYYKENLHHGRH--LLQRMSGLESVQPQRCENDEEFAHVSNFQGAQRSRSVGTLSKSEWEAATL 402
            .|...|..:...:  |:.||..:::                     :..|.:|...|   |||..
pombe   309 LDILNEEKNSETYGPLMDRMKVVDN---------------------EGHRGIGGQEK---EAAGF 349

  Fly   403 YLVCAFKK 410
            ||..||:|
pombe   350 YLAFAFEK 357

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Rnmt	NP_523568.2	Pox_MCEL	72..411	CDD:281307	111/345 (32%)
pcm1	NP_001342758.1	Pox_MCEL	52..358	CDD:281307	114/362 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	166	1.000	Domainoid score	I934
eggNOG	1	0.900	-	-		E1_KOG1975
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	166	1.000	Inparanoid score	I1212
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004895
OrthoInspector	1	1.000	-	-		oto100768
orthoMCL	1	0.900	-	-		OOG6_102244
Panther	1	1.100	-	-	LDO	PTHR12189
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R689
SonicParanoid	1	1.000	-	-		X3451
TreeFam	1	0.960	-	-
	12	11.850