Protein Alignment THG and Thg1l

DIOPT Version :10

• Sequence 1: NP_609737.1
• Gene: THG / 34876
• FlyBaseID: FBgn0283659
• Length: 286
• Species: Drosophila melanogaster
• Sequence 2: NP_001013988.1
• Gene: Thg1l / 303067
• RGDID: 1359513
• Length: 298
• Species: Rattus norvegicus
• Alignment Length: 265
• Identity: 150/265 - (56%)
• Similarity: 188/265 - (70%)
• Gaps: 19/265 - (7%)

  Fly     1 MACSRFEYVKSFEQDDSILPNVWIVIRIDGKKFHKFSKTHDFEKPNDENALNVMNAAATAVMQEF 65
            ||.|:||||:.||.||:.||:.|:|:|:||:.||:|::.|:|.||||..||::|...|..||||.
  Rat    30 MAKSKFEYVRDFEVDDTCLPHCWVVVRLDGRNFHRFAEKHNFAKPNDSRALHLMTKCAQTVMQEL 94

  Fly    66 RDIVLAYGQSDEYSFVFRKETAAFKRRSAKLLTYVTSLFSSSYVMQWSKWM-NLPLAYAPCFDGR 129
            .|||:||||||||||||||.:..||||::|.:|.|.|.|:||||..|..:. :.||.|.|.||||
  Rat    95 EDIVIAYGQSDEYSFVFRKRSNWFKRRASKFMTLVASQFASSYVFYWRDYFEDQPLLYPPGFDGR 159

  Fly   130 VVLYPSEQNLKDYLSWRQADVHVNNLYNTAFWKLVLEKGLTNQQAEAKLRGTFSADKNELLFQEF 194
            ||||||.|.|||||||||||.|:||||||.||.|:.:.|||..||:.:|:||.:|||||:||.||
  Rat   160 VVLYPSNQTLKDYLSWRQADCHINNLYNTVFWALIQQSGLTPVQAQQRLKGTLTADKNEILFSEF 224

  Fly   195 GINYNNLPAMYRKGTILLRKRV-------------ILGEK-----SRQAVVPLHEDLISSQFWKE 241
            .|||||.|.||||||:|:.::|             :.|||     :|..:|.|:.|||...||||
  Rat   225 HINYNNEPHMYRKGTVLVWQKVNEVRTQEIRLPAEMEGEKMAVTRTRTKLVALNCDLIGDAFWKE 289

  Fly   242 HTEIL 246
            |.|||
  Rat   290 HPEIL 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
THG	NP_609737.1	Thg1	6..134	CDD:461314	74/128 (58%)
		Thg1C	137..234	CDD:464167	60/114 (53%)
Thg1l	NP_001013988.1	Thg1	35..164	CDD:461314	74/128 (58%)
		Thg1C	167..283	CDD:464167	61/115 (53%)