DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and yahD

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_414852.1	Gene:	yahD / 947681	ECOCYCID:	G6183	Length:	201	Species:	Escherichia coli

Alignment Length:	92	Identity:	29/92 - (31%)
Similarity:	46/92 - (50%)	Gaps:	9/92 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 AVNENRISEVREILKLDADTVNAKDNDGYTPLHRAAYNNFVD-------MAKLLLQYHANPNART 112
            |..:..:|.|:|:|......||..::.|:|||..|...|  |       :.:|||::.|:|:...
E. coli   112 ACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLN--DGGIKQQAIVQLLLEHGASPHLTD 174

  Fly   113 ELGWTPLHSACKWNNADCAHLLLQFGA 139
            :.|.|||..|.:....:.|.||:..||
E. coli   175 KYGKTPLELARERGFEEIAQLLIAAGA 201

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	7/23 (30%)
		ANK	54..169	CDD:238125	29/92 (32%)
		Ank_5	67..120	CDD:290568	18/59 (31%)
		ANK repeat	81..112	CDD:293786	12/37 (32%)
		Ank_5	100..154	CDD:290568	15/40 (38%)
		ANK repeat	114..144	CDD:293786	10/26 (38%)
		ANK repeat	147..180	CDD:293786
yahD	NP_414852.1	ANKYR	<4..146	CDD:223738	11/33 (33%)
		ANK repeat	39..69	CDD:293786
		ANK repeat	72..101	CDD:293786
		ANK repeat	108..136	CDD:293786	7/23 (30%)
		Ank_2	112..201	CDD:403870	27/90 (30%)
		ANK repeat	138..174	CDD:293786	12/37 (32%)
		ANK repeat	176..201	CDD:293786	8/24 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
	1	1.000