DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and ANKMY2

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_064715.1	Gene:	ANKMY2 / 57037	HGNCID:	25370	Length:	441	Species:	Homo sapiens

Alignment Length:	163	Identity:	45/163 - (27%)
Similarity:	75/163 - (46%)	Gaps:	17/163 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ELIEEDKNPQSSIERMILWAVNENRISEVREILKLDADTVNAKDNDGYTPLHRAAYNNFVDMAKL 100
            ||.:|:|.        :|..:.:..:.|...:|......||..|.:|.|||..|||...:||.||
Human     8 ELTQEEKE--------LLEVIGKGTVQEAGTLLSSKNVRVNCLDENGMTPLMHAAYKGKLDMCKL 64

  Fly   101 LLQYHANPNA-RTELGWTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSNCRNT 164
            ||::.|:.|. :.|.|:|.|..|....|.|...::|:.||:.:..:...:|...:.|.|.. .:.
Human    65 LLRHGADVNCHQHEHGYTALMFAALSGNKDITWVMLEAGAETDVVNSVGRTAAQMAAFVGQ-HDC 128

  Fly   165 ATVL-------LLDRYIQPRKENNSEELASVIA 190
            .|::       .||.|.:|:..:...:|...:|
Human   129 VTIINNFFPRERLDYYTKPQGLDKEPKLPPKLA 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	5/26 (19%)
		ANK	54..169	CDD:238125	34/122 (28%)
		Ank_5	67..120	CDD:290568	22/53 (42%)
		ANK repeat	81..112	CDD:293786	15/31 (48%)
		Ank_5	100..154	CDD:290568	16/54 (30%)
		ANK repeat	114..144	CDD:293786	9/29 (31%)
		ANK repeat	147..180	CDD:293786	8/39 (21%)
ANKMY2	NP_064715.1	ANK repeat	16..43	CDD:293786	5/26 (19%)
		Ank_2	<30..>236	CDD:330894	39/133 (29%)
		ANK	31..132	CDD:238125	33/101 (33%)
		ANK repeat	45..77	CDD:293786	15/31 (48%)
		ANK 1	45..74		14/28 (50%)
		ANK repeat	79..110	CDD:293786	9/30 (30%)
		ANK 2	79..108		9/28 (32%)
		ANK 3	159..188		1/3 (33%)
		zf-MYND	320..357	CDD:307734
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	374..441
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910