DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and tnks2

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_001017008.2	Gene:	tnks2 / 549762	XenbaseID:	XB-GENE-968819	Length:	1167	Species:	Xenopus tropicalis

Alignment Length:	160	Identity:	55/160 - (34%)
Similarity:	77/160 - (48%)	Gaps:	27/160 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 DDADELIEEDKNPQSSIERMILWAVNENRISEVREILKLDADTVNAKDNDG--YTPLHRAAYNNF 94
            :.|.||.|..:|  ..:||             ||::  ::||.||::|..|  .||||.||....
Frog    24 EPARELFEACRN--GDVER-------------VRKL--VNADNVNSRDTAGRKSTPLHFAAGFGR 71

  Fly    95 VDMAKLLLQYHANPNARTELGWTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLH---ITA 156
            .|:.:.|||..||.:||.:.|..|||:||.:.:|:...|||:.|||.||..:...||||   |..
Frog    72 KDVVEHLLQSGANVHARDDGGLIPLHNACSFGHAEVVSLLLRHGADPNARDNWNYTPLHEAAIKG 136

  Fly   157 TVSNCRNTATVLLLDRYIQPRKENNSEELA 186
            .:..|     ::||.....|...|.....|
Frog   137 KIDVC-----IVLLQHGADPTIRNTDSRTA 161

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	6/26 (23%)
		ANK	54..169	CDD:238125	43/119 (36%)
		Ank_5	67..120	CDD:290568	22/54 (41%)
		ANK repeat	81..112	CDD:293786	14/32 (44%)
		Ank_5	100..154	CDD:290568	26/56 (46%)
		ANK repeat	114..144	CDD:293786	14/29 (48%)
		ANK repeat	147..180	CDD:293786	9/35 (26%)
tnks2	NP_001017008.2	PTZ00322	28..>114	CDD:140343	38/102 (37%)
		ANK repeat	61..89	CDD:293786	13/27 (48%)
		PHA02876	<74..>438	CDD:165207	33/93 (35%)
		ANK repeat	91..122	CDD:293786	15/30 (50%)
		ANK repeat	124..155	CDD:293786	9/35 (26%)
		ANK repeat	214..242	CDD:293786
		ANK repeat	244..275	CDD:293786
		ANK repeat	277..308	CDD:293786
		ANKYR	310..>472	CDD:223738
		ANK repeat	366..398	CDD:293786
		ANK repeat	400..431	CDD:293786
		ANK repeat	434..522	CDD:293786
		PHA03095	495..>804	CDD:222980
		ANK repeat	529..557	CDD:293786
		ANK repeat	559..590	CDD:293786
		ANK repeat	592..623	CDD:293786
		ANK repeat	645..675	CDD:293786
		ANK repeat	682..710	CDD:293786
		ANK repeat	712..743	CDD:293786
		ANK repeat	745..776	CDD:293786
		SAM_tankyrase1,2	872..937	CDD:188923
		tankyrase_like	940..1161	CDD:238718
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910