DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and Asb12

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_001032444.1	Gene:	Asb12 / 503446	RGDID:	1561142	Length:	308	Species:	Rattus norvegicus

Alignment Length:	174	Identity:	51/174 - (29%)
Similarity:	73/174 - (41%)	Gaps:	48/174 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 ISEVREILKL--------DADTVNAK-------DNDGYT---PLHRAAYNNFVDMAKLLLQYHAN 107
            :.::.:|..|        ||||...:       |||..|   .||:..|..|:
  Rat     3 LMDIAKIFSLLQPEKEEEDADTGEKQALNQAVYDNDSCTLDHLLHQERYKRFI------------ 55

  Fly   108 PNARTELGW----TPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSNCRNTATVL 168
             |:|:  ||    |||..|..:.:.||..:||:.||||::.....|||| .|| ||:.......:
  Rat    56 -NSRS--GWGIPGTPLRLAASYGHLDCVKVLLEHGADVDSLDVKAQTPL-FTA-VSHGHLECVRI 115

  Fly   169 LLDRYIQPRKE--NNSEELASVIARRTGMSFPIFES----GEEA 206
            ||:....|...  ||...:  :.|.|.| :|.|.:.    |.||
  Rat   116 LLEAGACPSGSIYNNCSPV--LTASRDG-AFAILQELLGHGAEA 156

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	6/32 (19%)
		ANK	54..169	CDD:238125	38/129 (29%)
		Ank_5	67..120	CDD:290568	20/74 (27%)
		ANK repeat	81..112	CDD:293786	7/33 (21%)
		Ank_5	100..154	CDD:290568	20/57 (35%)
		ANK repeat	114..144	CDD:293786	14/33 (42%)
		ANK repeat	147..180	CDD:293786	11/34 (32%)
Asb12	NP_001032444.1	ANK repeat	66..94	CDD:293786	12/27 (44%)
		Ank_2	68..159	CDD:403870	31/94 (33%)
		ANK repeat	96..160	CDD:293786	21/66 (32%)
		ANK repeat	173..199	CDD:293786
		Ank	175..199	CDD:394980
		SOCS_box	268..306	CDD:400074
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910