DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and Patsas

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_001356957.1	Gene:	Patsas / 34634	FlyBaseID:	FBgn0029137	Length:	613	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	45/148 - (30%)
Similarity:	73/148 - (49%)	Gaps:	9/148 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 SGWDDDADELIEEDKNPQSSIERMILWAVNEN-RISEVREIL-KLDADTVNAKDNDGYTPLHRAA 90
            ||.:|..:.|:.|..:..:::....::.:.:| .:|||..:: |...:.::|:|..||||.|..|
  Fly    93 SGVEDHENVLLFEGLDGATTVSLDDIFDIIKNGEVSEVENLVDKFGMECLSARDRHGYTPAHWIA 157

  Fly    91 YNNFVDMAKLLLQYHAN---PNARTELGWTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPL 152
            .|..|.:.:.|::..|.   |...|: |..|:|.||:..:|....:|||.|..|||......|||
  Fly   158 LNGNVQLMRYLIERTAPIDLPCLGTQ-GPRPIHWACRKGHASVVQVLLQAGVAVNAADFKGLTPL 221

  Fly   153 HITATVSNCRNTATVLLL 170
            |:.....   .|||...|
  Fly   222 HLACMYG---RTATAAYL 236

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	6/28 (21%)
		ANK	54..169	CDD:238125	39/119 (33%)
		Ank_5	67..120	CDD:290568	17/56 (30%)
		ANK repeat	81..112	CDD:293786	11/33 (33%)
		Ank_5	100..154	CDD:290568	20/56 (36%)
		ANK repeat	114..144	CDD:293786	12/29 (41%)
		ANK repeat	147..180	CDD:293786	8/24 (33%)
Patsas	NP_001356957.1	ANKYR	113..306	CDD:223738	40/128 (31%)
		ANK repeat	148..181	CDD:293786	11/32 (34%)
		ANK repeat	187..214	CDD:293786	12/26 (46%)
		ANK repeat	216..247	CDD:293786	8/24 (33%)
		ANK repeat	249..280	CDD:293786
		ANK repeat	282..314	CDD:293786
		Ank_4	283..336	CDD:316185
		DHHC	455..567	CDD:334580
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.910