DRSC/TRiP Functional Genomics Resources

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Protein Alignment l(2)35Be and ZDHHC17

DIOPT Version :9

Sequence 1:NP_609735.1 Gene:l(2)35Be / 34874 FlyBaseID:FBgn0261881 Length:215 Species:Drosophila melanogaster
Sequence 2:NP_056151.2 Gene:ZDHHC17 / 23390 HGNCID:18412 Length:632 Species:Homo sapiens


Alignment Length:199 Identity:50/199 - (25%)
Similarity:80/199 - (40%) Gaps:30/199 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    28 SGWD----------DDADELIE---EDKNPQSSIERMILWAVNENRISEVREILKLDA--DTVNA 77
            |.||          :...||:|   :.:.|......::.||...|||..|:..:...|  |.:..
Human    57 STWDIVKATQYGIYERCRELVEAGYDVRQPDKENVTLLHWAAINNRIDLVKYYISKGAIVDQLGG 121

  Fly    78 KDNDGYTPLHRAAYNNFVDMAKLLLQYHANPNARTELGWTPLHSACKWNNADCAHLLLQFGADVN 142
            ..|.  ||||.|.....:.|...|::|.|:|:.....|.:.:|.|.::.:......|:..|.||:
Human   122 DLNS--TPLHWATRQGHLSMVVQLMKYGADPSLIDGEGCSCIHLAAQFGHTSIVAYLIAKGQDVD 184

  Fly   143 AESDGKQTPL----HITATVSNCRNTAT----VLLLDRYIQPRKENNSEELASVIARRTGMSFPI 199
            .......|||    :.|.:|...|...|    |.|.|:|     ..|:....:|:|..|.:...:
Human   185 MMDQNGMTPLMWAAYRTHSVDPTRLLLTFNVSVNLGDKY-----HKNTALHWAVLAGNTTVISLL 244

  Fly   200 FESG 203
            .|:|
Human   245 LEAG 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
l(2)35BeNP_609735.1 ANK repeat 52..79 CDD:293786 8/28 (29%)
ANK 54..169 CDD:238125 34/124 (27%)
Ank_5 67..120 CDD:290568 14/54 (26%)
ANK repeat 81..112 CDD:293786 10/30 (33%)
Ank_5 100..154 CDD:290568 14/57 (25%)
ANK repeat 114..144 CDD:293786 7/29 (24%)
ANK repeat 147..180 CDD:293786 11/40 (28%)
ZDHHC17NP_056151.2 Necessary and sufficient for interaction with DNAJC5 and SNAP25. /evidence=ECO:0000250|UniProtKB:Q80TN5 11..305 50/199 (25%)
ANK repeat 89..120 CDD:293786 8/30 (27%)
Ank_2 94..187 CDD:403870 26/94 (28%)
ANK repeat 122..154 CDD:293786 11/33 (33%)
ANK repeat 156..187 CDD:293786 7/30 (23%)
Ank_2 161..255 CDD:403870 23/93 (25%)
ANK repeat 189..221 CDD:293786 9/31 (29%)
ANK repeat 224..255 CDD:293786 6/25 (24%)
Ank_2 229..>286 CDD:423045 5/20 (25%)
DHHC 438..568 CDD:396215
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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