DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and daf-25

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	NP_490719.1	Gene:	daf-25 / 171623	WormBaseID:	WBGene00000917	Length:	388	Species:	Caenorhabditis elegans

Alignment Length:	163	Identity:	36/163 - (22%)
Similarity:	68/163 - (41%)	Gaps:	20/163 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 EEDKNPQSSIERMILWAVNENRISEVREILKLDADTVNAKDNDGYTPLHRAAYNNFVDMAKLLLQ 103
            |..|:|       :..|:::|.......:||....... :|..|.:.|..|||...:.:.:..::
Worm     6 EAPKSP-------LFEAIDKNDTEAALALLKTKEQAAQ-RDPSGMSVLAAAAYRGNLTLVEKAIE 62

  Fly   104 YHANPNARTELG--WTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSN--C--- 161
            ...:.|.:|: |  :|||..|......|...||:..||.:...:...:|...:.|.|.:  |
Worm    63 LKCDVNDKTD-GTLYTPLMFAALSGKQDVCRLLMDSGARMYLVNGIGKTASELAAFVGHHECVAI 126

  Fly   162 -RNTATVLLLDRYIQPR---KENNSEELASVIA 190
             .|..|:.:::..::|:   |...:||....:|
Worm   127 INNHITIDVIEDLLRPKVNGKYEGAEEYPDELA 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	4/26 (15%)
		ANK	54..169	CDD:238125	28/122 (23%)
		Ank_5	67..120	CDD:290568	13/54 (24%)
		ANK repeat	81..112	CDD:293786	6/30 (20%)
		Ank_5	100..154	CDD:290568	13/55 (24%)
		ANK repeat	114..144	CDD:293786	10/31 (32%)
		ANK repeat	147..180	CDD:293786	8/41 (20%)
daf-25	NP_490719.1	ANK	9..127	CDD:238125	28/126 (22%)
		ANK repeat	10..38	CDD:293786	5/35 (14%)
		Ank_2	12..105	CDD:289560	22/94 (23%)
		ANK repeat	40..72	CDD:293786	6/31 (19%)
		ANK repeat	74..105	CDD:293786	9/30 (30%)
		Ank_2	79..>134	CDD:289560	13/54 (24%)
		zf-MYND	321..357	CDD:280009
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910