DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and AgaP_AGAP008928

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	XP_319681.2	Gene:	AgaP_AGAP008928 / 1279899	VectorBaseID:	AGAP008928	Length:	564	Species:	Anopheles gambiae

Alignment Length:	169	Identity:	52/169 - (30%)
Similarity:	81/169 - (47%)	Gaps:	16/169 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DEKSQVEKLRHAKVPRGMFVSGWDDDADELIEEDKNP---QSSIERMILWAVNENRISEVREIL- 68
            :|.........||.|.      .:.|::.|...|.:.   |||::. |...:....:|||..::
Mosquito    29 EESDHPHHPEEAKTPT------QEKDSNLLARTDSSEVLIQSSMDD-IFDVIKSGELSEVENLVE 86

  Fly    69 KLDADTVNAKDNDGYTPLHRAAYNNFVDMAKLLLQYHAN---PNARTELGWTPLHSACKWNNADC 130
            |:..:.::|:|..||||.|.||.:..|:|.:.|::.:|.   |...|: |..|:|.||:..:|..
Mosquito    87 KVGQEALSARDKHGYTPAHWAALDGNVEMMRYLVERNAPVDLPCLGTQ-GPRPIHWACRKGHAAV 150

  Fly   131 AHLLLQFGADVNAESDGKQTPLHITATVSNCRNTATVLL 169
            ..:|||.|..|||......||| :||.:.....||..||
Mosquito   151 VQVLLQAGVAVNAADFKGLTPL-MTACMYGRTATAAYLL 188

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	6/27 (22%)
		ANK	54..169	CDD:238125	39/118 (33%)
		Ank_5	67..120	CDD:290568	18/56 (32%)
		ANK repeat	81..112	CDD:293786	12/33 (36%)
		Ank_5	100..154	CDD:290568	20/56 (36%)
		ANK repeat	114..144	CDD:293786	12/29 (41%)
		ANK repeat	147..180	CDD:293786	9/23 (39%)
AgaP_AGAP008928	XP_319681.2	ANKYR	64..288	CDD:223738	44/128 (34%)
		ANK repeat	99..132	CDD:293786	12/32 (38%)
		ANK	99..128	CDD:197603	11/28 (39%)
		ANK	138..253	CDD:238125	21/52 (40%)
		ANK repeat	138..165	CDD:293786	12/26 (46%)
		ANK repeat	167..198	CDD:293786	9/23 (39%)
		ANK repeat	200..231	CDD:293786
		zf-DHHC	321..544	CDD:303066
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910