DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment l(2)35Be and ankrd49

DIOPT Version :9

Sequence 1:	NP_609735.1	Gene:	l(2)35Be / 34874	FlyBaseID:	FBgn0261881	Length:	215	Species:	Drosophila melanogaster
Sequence 2:	XP_004912165.2	Gene:	ankrd49 / 100487113	XenbaseID:	XB-GENE-479219	Length:	776	Species:	Xenopus tropicalis

Alignment Length:	235	Identity:	48/235 - (20%)
Similarity:	85/235 - (36%)	Gaps:	76/235 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 DEKSQVEKLRHAKVPRGMFVSGWDDDADEL------------IEEDKNPQSSIERMILWAVNENR 60
            ||.|:..||             |..:.|.|            |...:.|:|:  |.....|.||:
Frog   219 DEYSEPAKL-------------WRVEKDHLYSISLSTPTNPCIITIQTPKST--RPNTLPVQENK 268

  Fly    61 ISEVREILKLDADTVNAKDND----GYTP-----LHRAAYN-----NFVDMAKLLLQYHANPNAR 111
            ::|| .:....:.|...||.:    .|||     ..::.||     :::...|.:: :.::.:..
Frog   269 MTEV-ALATSFSTTEEPKDPNLDSLEYTPQDSRGSSKSNYNQADKISYIADRKFVV-FESSLDKL 331

  Fly   112 TELGWTPLHSACKWNNADCAHLLLQFGADVNAESDGKQTPLHITATVSN----CRNTATVLLLDR 172
            ..|      ..|:.|..:            ..|:..|:...||..::.|    |||....|..:.
Frog   332 LRL------IPCQHNEGE------------KCEAPIKEIQKHIDGSMVNIQLLCRNNHKSLYWNS 378

  Fly   173 YIQPRKEN----NSEELASVIARRTGMSFPIFESGEEAYD 208
              ||...:    |....:|::.  :|:|   |:..:|.||
Frog   379 --QPMTSDMAVGNILMSSSIVL--SGLS---FQKVKEMYD 411

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
l(2)35Be	NP_609735.1	ANK repeat	52..79	CDD:293786	6/26 (23%)
		ANK	54..169	CDD:238125	25/132 (19%)
		Ank_5	67..120	CDD:290568	10/66 (15%)
		ANK repeat	81..112	CDD:293786	6/44 (14%)
		Ank_5	100..154	CDD:290568	5/53 (9%)
		ANK repeat	114..144	CDD:293786	3/29 (10%)
		ANK repeat	147..180	CDD:293786	10/36 (28%)
ankrd49	XP_004912165.2	THAP	5..94	CDD:398893
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4334
OMA	1	1.010	-	-		QHG48821
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007458
OrthoInspector	1	1.000	-	-		oto104003
Panther	1	1.100	-	-	LDO	PTHR24144
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4168
SonicParanoid	1	1.000	-	-		X5588
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190