DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCTN5-p25 and Dctn5

DIOPT Version :9

Sequence 1:	NP_723893.1	Gene:	DCTN5-p25 / 34873	FlyBaseID:	FBgn0040228	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_067621.3	Gene:	Dctn5 / 59288	MGIID:	1891689	Length:	182	Species:	Mus musculus

Alignment Length:	182	Identity:	106/182 - (58%)
Similarity:	138/182 - (75%)	Gaps:	5/182 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGK 65
            ||:.:..|:|.||:||||||||||.:||||||||:||||.|:.:..||||||||||.||:||:..
Mouse     1 MELGELLYNKSEYIETASGNKVSRQSVLCGSQNIVLNGKTIIMNDCIIRGDLANVRVGRHCVVKS 65

  Fly    66 NSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIED 130
            .||||||:|:||||:||||:|:|:|||:.|..||:||.|||||::|||.:|||||||||||.|.|
Mouse    66 RSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIGSYVHVGKNCVIGRRCVLKDCCKILD 130

  Fly   131 GAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFV 182
            ..||||||.|..:..::....:..|:     :|...|:.||:.|||:|:.|:
Mouse   131 NTVLPPETVVPPFTVFSGCPGLFSGE-----LPECTQELMIDVTKSYYQKFL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN5-p25	NP_723893.1	LbH_Dynactin_5	13..178	CDD:100049	99/164 (60%)
Dctn5	NP_067621.3	LbH_Dynactin_5	13..173	CDD:100049	99/164 (60%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835042
Domainoid	1	1.000	151	1.000	Domainoid score	I4361
eggNOG	1	0.900	-	-		E1_KOG3121
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10998
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3483
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54761
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007318
OrthoInspector	1	1.000	-	-		oto94056
orthoMCL	1	0.900	-	-		OOG6_103929
Panther	1	1.100	-	-	LDO	PTHR46126
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4294
SonicParanoid	1	1.000	-	-		X5427
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790