DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment DCTN5-p25 and dctn5

DIOPT Version :9

Sequence 1:	NP_723893.1	Gene:	DCTN5-p25 / 34873	FlyBaseID:	FBgn0040228	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001002497.1	Gene:	dctn5 / 436770	ZFINID:	ZDB-GENE-040718-201	Length:	182	Species:	Danio rerio

Alignment Length:	182	Identity:	107/182 - (58%)
Similarity:	136/182 - (74%)	Gaps:	5/182 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MEIPDTYYSKDEYVETASGNKVSRHTVLCGSQNIILNGKVIVQSGAIIRGDLANVRTGRYCVIGK 65
            ||:.:..|:|.||:||||||||||.:||||||||:||||.||.:..||||||||||.||:|||..
Zfish     1 MELCEILYNKAEYIETASGNKVSRQSVLCGSQNIVLNGKTIVMNDCIIRGDLANVRVGRHCVIKS 65

  Fly    66 NSVIRPPYKQFSKGIAFFPMHVGEHVFVGEGAVVSAATIGSYVYIGKNAIIGRRCVLKDCCVIED 130
            .||||||:|:||||:||||:|:|:|||:.|..||:||.|.|||:||||.:|||||||||||.|.|
Zfish    66 RSVIRPPFKKFSKGVAFFPLHIGDHVFIEEDCVVNAAQIRSYVHIGKNCVIGRRCVLKDCCKILD 130

  Fly   131 GAVLPPETTVSSYMRYTARGTIEGGQGNPYFVPAAMQDEMINYTKSFYEHFV 182
            ..||||.|.|..:..::....:..|:     :|...|:.||:.|||:|:.|:
Zfish   131 NTVLPPGTVVPPFTVFSGCPGLFSGE-----LPECTQELMIDVTKSYYQKFL 177

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCTN5-p25	NP_723893.1	LbH_Dynactin_5	13..178	CDD:100049	100/164 (61%)
dctn5	NP_001002497.1	LbH_Dynactin_5	13..173	CDD:100049	100/164 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578179
Domainoid	1	1.000	136	1.000	Domainoid score	I4911
eggNOG	1	0.900	-	-		E1_KOG3121
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10998
Inparanoid	1	1.050	225	1.000	Inparanoid score	I3476
OMA	1	1.010	-	-		QHG54761
OrthoDB	1	1.010	-	-		D1270774at2759
OrthoFinder	1	1.000	-	-		FOG0007318
OrthoInspector	1	1.000	-	-		oto38961
orthoMCL	1	0.900	-	-		OOG6_103929
Panther	1	1.100	-	-	LDO	PTHR46126
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4294
SonicParanoid	1	1.000	-	-		X5427
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800