Protein Alignment mol and DUOXA1

DIOPT Version :9

• Sequence 1: NP_001036362.1
• Gene: mol / 34872
• FlyBaseID: FBgn0086711
• Length: 474
• Species: Drosophila melanogaster
• Sequence 2: NP_001263193.1
• Gene: DUOXA1 / 90527
• HGNCID: 26507
• Length: 483
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 129/419 - (30%)
• Similarity: 188/419 - (44%)
• Gaps: 74/419 - (17%)

  Fly    28 DVSIVAVSVLFATFYVAFLVIFPGVR-KQKFTTFSTVTLSLFVGLVILITRLGSAWHVAHATIIA 91
            |.::.::.::|.|....|:||.||:| |.:......|..|||:|..||.....|.|.|...:...
Human    21 DTTLASIIMIFLTALATFIVILPGIRGKTRLFWLLRVVTSLFIGAAILAVNFSSEWSVGQVSTNT 85

  Fly    92 PYKAFSREKLPARIGTHIGLMHVNVTLTAIPIG--NWTPPDIDYNERFTWEGANDMSANYRHALQ 154
            .|||||.|.:.|.||..:||..||:|||..|:.  |.|   |:|||.|||....:.:..|..||:
Human    86 SYKAFSSEWISADIGLQVGLGGVNITLTGTPVQQLNET---INYNEEFTWRLGENYAEEYAKALE 147

  Fly   155 RGLPFPILTVAEYFSLGREGFSWGGQYRAAGYFASIMLWASLASWLLMNLLL-IAVPRYGAYMKA 218
            :|||.|:|.:||.|: .|.......|||.||::.|.|||.:...|||.|::| :.|..||.||..
Human   148 KGLPDPVLYLAEKFT-PRSPCGLYRQYRLAGHYTSAMLWVAFLCWLLANVMLSMPVLVYGGYMLL 211

  Fly   219 LTG-----ALL---VCTTVGYHCLLPKRPLSIHLEGGRLEFHFGWCYWLVLVAGILCFIAGVLIS 275
            .||     |||   :.|::       ..|..:||....|..|.|..:|:.|..|:||.:.|:.::
Human   212 ATGIFQLLALLFFSMATSL-------TSPCPLHLGASVLHTHHGPAFWITLTTGLLCVLLGLAMA 269

  Fly   276 IIDLVWPHTFSTVLEVYYGTPYDRHVILEESSD------VRYRKPRNSRSLEDPPGLGSRILRRL 334
            :...:.||.    |:.::....|...:||.|.:      .|||...:|...:|.|
Human   270 VAHRMQPHR----LKAFFNQSVDEDPMLEWSPEEGGLLSPRYRSMADSPKSQDIP---------- 320

  Fly   335 SSKARDLQPGTAPRRDS----------PAGVSSSGGV-----------------ENKGFQSDAPK 372
            .|:|...:....|||.|          ||.:|:..|.                 ..|..:...|.
Human   321 LSEASSTKAYYRPRRLSLVPADVRGLAPAALSALPGALLAQAWRALLPGLRCPKAGKESRLGPPH 385

  Fly   373 SPWRY-PFRRSQQMAQQQHSHPLHQHPLQ 400
            ||||: |....::.|:.....|   .||:
Human   386 SPWRFGPEGCEERWAEHTGDSP---RPLR 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
mol	NP_001036362.1	DuoxA	18..289	CDD:287209	97/272 (36%)
DUOXA1	NP_001263193.1	DuoxA	11..283	CDD:402003	98/276 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142562
Domainoid	1	1.000	159	1.000	Domainoid score	I4092
eggNOG	1	0.900	-	-		E1_KOG3921
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H16043
Inparanoid	1	1.050	165	1.000	Inparanoid score	I4188
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D360121at33208
OrthoFinder	1	1.000	-	-		FOG0003131
OrthoInspector	1	1.000	-	-		otm41042
orthoMCL	1	0.900	-	-		OOG6_106442
Panther	1	1.100	-	-	O	PTHR31158
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R7905
SonicParanoid	1	1.000	-	-		X3013
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	14	13.790