Protein Alignment CG15279 and SLC6A9

DIOPT Version :10

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_054194404.1
• Gene: SLC6A9 / 6536
• HGNCID: 11056
• Length: 712
• Species: Homo sapiens
• Alignment Length: 614
• Identity: 209/614 - (34%)
• Similarity: 323/614 - (52%)
• Gaps: 56/614 - (9%)

  Fly    27 ISTNSPALRDN-SDDQEAAKVPE--ERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAF 88
            ::.:|.|:..| :...||.|..:  :|..||..:||:::.:..:||||||||||:....||||||
Human    74 MAQHSLAMAQNGAVPSEATKRDQNLKRGNWGNQIEFVLTSVGYAVGLGNVWRFPYLCYRNGGGAF 138

  Fly    89 LIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVFDLCPAMKGVGAGQAFQVFMLSTYYAALVAII 153
            :.||.|:|...|.|::::|:..|||:|:|.:.|:.:.|..||||.|.......:..||..::.|.
Human   139 MFPYFIMLIFCGIPLFFMELSFGQFASQGCLGVWRISPMFKGVGYGMMVVSTYIGIYYNVVICIA 203

  Fly   154 GRYFIESFRNPLPWSTCRAEWGIHCINSAPDASNWSQLESNDQRPQ------NYTMKSQNDRVIT 212
            ..||..|..:.|||:.|...|..|......||||.    :|..||.      ::.:.....|...
Human   204 FYYFFSSMTHVLPWAYCNNPWNTHDCAGVLDASNL----TNGSRPAALPSNLSHLLNHSLQRTSP 264

  Fly   213 SSEWY--FVKEVLHEKPNIEEGIGLPNWELVIG-LFIAWSCVFFIIRRGVKSSGKASYFLALFPY 274
            |.|::  :|.::..:..|..| :.||    ::| |.::|..||..:.||||||||..||.|.|||
Human   265 SEEYWRLYVLKLSDDIGNFGE-VRLP----LLGCLGVSWLVVFLCLIRGVKSSGKVVYFTATFPY 324

  Fly   275 VIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFG 339
            |::.:|.||.|||.|:.|||.|::.|||.|||:.|||..|.:|.||||...:|.:|..:|:|||.
Human   325 VVLTILFVRGVTLEGAFDGIMYYLTPQWDKILEAKVWGDAASQIFYSLGCAWGGLITMASYNKFH 389

  Fly   340 HNVHRDAAIVTGLDTMTSLLAGFTIFGILGHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKN 404
            :|.:||:.|::..:..||:.|||.||.|||.:|:.:|. |:..|...|.||||::||:|:.....
Human   390 NNCYRDSVIISITNCATSVYAGFVIFSILGFMANHLGV-DVSRVADHGPGLAFVAYPEALTLLPI 453

  Fly   405 LPQIFSVLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPNFGQW------QCSLLIAVVSFFIGLMY 463
            .| ::|:|||.||.:||:|:...:....||||.|...|  :|      ..:|.:||..|.:|:..
Human   454 SP-LWSLLFFFMLILLGLGTQFCLLETLVTAIVDEVGN--EWILQKKTYVTLGVAVAGFLLGIPL 515

  Fly   464 ITPGGQYMLTLVDFFGASMIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIIT 528
            .:..|.|.|.|:|.:.||...:|:.......|.:|||.....:||:.|||....|::::||..::
Human   516 TSQAGIYWLLLMDNYAASFSLVVISCIMCVAIMYIYGHRNYFQDIQMMLGFPPPLFFQICWRFVS 580

  Fly   529 P-LIMTVILIYFYATYQPLTYNNIVYPNWSYSIGWLITAFGILQ----LPIWMIVAIVRDPGQTL 588
            | :|.....::......||.:.::  |..:..:..|....|:.:    .|        ..|.:|.
Human   581 PAIIFLQAQVHRRLPQNPLHFASL--PERNVLLHQLPQRGGVPEHDPPTP--------PSPARTY 635

  Fly   589 GAKIRGAFTPKKN----------WGPSDP 607
            |.::|....|:..          |.|..|
Human   636 GPQVRVREVPRARRQRSPNPAPLWAPPSP 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:444915	199/567 (35%)
SLC6A9	XP_054194404.1	SLC5-6-like_sbd	84..586	CDD:444915	193/514 (38%)
		PHA03247	<615..676	CDD:223021	10/58 (17%)