DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15279 and slc6a16b

DIOPT Version :9

Sequence 1:	NP_609726.1	Gene:	CG15279 / 34863	FlyBaseID:	FBgn0028886	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001103944.1	Gene:	slc6a16b / 567809	ZFINID:	ZDB-GENE-070424-95	Length:	676	Species:	Danio rerio

Alignment Length:	699	Identity:	191/699 - (27%)
Similarity:	315/699 - (45%)	Gaps:	143/699 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    28 STNSPALRDNSDDQEAAK------VPEERAT--WGKGVEFLMSCIAMSVGLGNVWRFPFTALDNG 84
            |...|...|...|:...:      ||.|.|.  |...||:.::.:..|||||||||||:....||
Zfish     3 SAKPPLPADGQQDEVELRLGLEPEVPLETARDGWDSKVEYFLAQVGFSVGLGNVWRFPYLCHQNG 67

  Fly    85 GGAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVF-DLCPAMKGVGAGQAFQVFMLSTYYAA 148
            ||||::.|::::.|:|.|:::||:..||...:||:.|: .:.|.:.|:|.......|.::.||..
Zfish    68 GGAFILLYVVLMALVGVPLFFLELAAGQSIRQGSIGVWRHISPKLVGIGYSSCVVCFFVALYYNV 132

  Fly   149 LVAIIGRYFIESFRNPLPWSTCRAEWGI---HCINSAPDASNWSQLESNDQRPQNYTMKSQNDRV 210
            ::.....|...||:.||||..|..|...   .|..|:|
Zfish   133 IIGWSIFYLGNSFQYPLPWEKCPTEGNSTVKECAASSP--------------------------- 170

  Fly   211 ITSSEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYV 275
             |:..||  ::.|....:|:| .|..|:.|...|..||..|...:.:|:|||||..||.::||||
Zfish   171 -TAYFWY--RKALDITDSIDE-TGEFNFILTGCLLAAWVIVCLAMYKGIKSSGKVMYFSSVFPYV 231

  Fly   276 IMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGH 340
            ::...|:|.|||.|:.:||.:...|:.....|.:||..|.||.|::|.:.||::|.|||:|...:
Zfish   232 VLLCFLIRGVTLDGASEGIKFMFYPRLEIWADVQVWRQAATQVFFALGLGFGSVIAYSSYNPRNN 296

  Fly   341 NVHRDAAIVTGLDTMTSLLAGFTIFGILGHLAHEIGTD--------------------------D 379
            |.||||..|:|::.|||:||...:|.:||..|..|..:                          |
Zfish   297 NCHRDAFTVSGVNFMTSVLATLVVFAVLGFRAKTIAAECVKRNLKALLKVTSSAPLPVLSINASD 361

  Fly   380 IGSV-------------------------------VKGG---AGLAFISYPDAIAKFKNLPQIFS 410
            :.|:                               ::.|   .|||||::.:|:..|...| .:|
Zfish   362 VESISLDEYANWYSTQGMELSISDYNITACSLEDELRQGVEETGLAFIAFTEAMTLFPGSP-FWS 425

  Fly   411 VLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPNFGQWQ-----CSLLIAVVSFFIGLMYITPGGQY 470
            .||||||..||:.:.....:..:|.:.|.|......:     ||   ..|.|.|||::....|.|
Zfish   426 ALFFLMLLNLGLSTMFGTMAGILTPLTDTFKTLRNHKLIFTICS---CTVGFVIGLVFTQRCGNY 487

  Fly   471 MLTLVDFFGASMIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVI 535
            .:|:.|.:.|::..:::.|.:..::.|:||.||..:|::.||.|.|.:.::..|..:.|:.|..:
Zfish   488 FVTMFDDYSATLPLIIVVIFQTISVSWVYGADRFLEDLKQMLNRPVPVIYKYLWKFVCPIAMLGL 552

  Fly   536 L------------IYFYATYQPLTYNNIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRDP-GQT 587
            |            .|.....:..:..::.||:|:.::..::.....|.:||..|.:::.:. ||:
Zfish   553 LGASLLKMILKRPEYSAWNREKASKEDLPYPDWALAVLIILIIIASLPVPIGYIHSLLLERLGQS 617

  Fly   588 LGAKIRGAFTP-----------------KKNWGPSDPLLREQYHKEIEN 619
             .|.....:||                 :.:...|.|||...::..::|
Zfish   618 -PADTEARYTPCATTDTDLTPLSTLPPSRDDLNSSHPLLEGNHNSHLQN 665

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	177/631 (28%)
slc6a16b	NP_001103944.1	SLC6sbd-B0AT-like	33..607	CDD:271364	172/608 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910