Protein Alignment CG15279 and SLC6A17

DIOPT Version :10

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001010898.1
• Gene: SLC6A17 / 388662
• HGNCID: 31399
• Length: 727
• Species: Homo sapiens
• Alignment Length: 690
• Identity: 206/690 - (29%)
• Similarity: 330/690 - (47%)
• Gaps: 141/690 - (20%)

  Fly     4 TQRNHQN---LAFVGD--------DGRSTASTV--EISTNSPALRDNSDDQEAAKVPEERATWGK 55
            |||.|.:   ...|.|        |.:.:...|  |......|:.:..|       .|:|..|..
Human     8 TQREHSSEHVTESVADLLALEEPVDYKQSVLNVAGEAGGKQKAVEEELD-------AEDRPAWNS 65

  Fly    56 GVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVK 120
            .::::::.|..||||||:||||:....|||||:|:|||::|.:||.|:::||:.:||...|||:.
Human    66 KLQYILAQIGFSVGLGNIWRFPYLCQKNGGGAYLVPYLVLLIIIGIPLFFLELAVGQRIRRGSIG 130

  Fly   121 VFD-LCPAMKGVGAGQAFQVFMLSTYYAALVAIIGRYFIESFRNPLPWSTCRAEWGIHCINSAPD 184
            |:. :||.:.|:|.........:..||..::.....||.:||:.|||||.|            |.
Human   131 VWHYICPRLGGIGFSSCIVCLFVGLYYNVIIGWSIFYFFKSFQYPLPWSEC------------PV 183

  Fly   185 ASNWS--QLESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIA 247
            ..|.|  .:|:..::..           .|:..||  :|.|....:|.|..|| ||::.:.|.:|
Human   184 VRNGSVAVVEAECEKSS-----------ATTYFWY--REALDISDSISESGGL-NWKMTLCLLVA 234

  Fly   248 WSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWY 312
            ||.|...:.:|::||||..||.:|||||::...|||.:.|.|::|||.:...|:..|:|||:||.
Human   235 WSIVGMAVVKGIQSSGKVMYFSSLFPYVVLACFLVRGLLLRGAVDGILHMFTPKLDKMLDPQVWR 299

  Fly   313 AAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGILG-------- 369
            .|.||.|::|.:.||.:|.:||:||..:|.|.|||:|:.::..||:||...:|.:||
Human   300 EAATQVFFALGLGFGGVIAFSSYNKQDNNCHFDAALVSFINFFTSVLATLVVFAVLGFKANIMNE 364

  Fly   370 -------------------------------HLAHE-------------------IG------TD 378
                                           ||..:                   :|      .|
Human   365 KCVVENAEKILGYLNTNVLSRDLIPPHVNFSHLTTKDYMEMYNVIMTVKEDQFSALGLDPCLLED 429

  Fly   379 DIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPNF 443
            ::...|: |.|||||::.:|:..|...| .:||:|||||..||:||.|...:...|.|.|.| ..
Human   430 ELDKSVQ-GTGLAFIAFTEAMTHFPASP-FWSVMFFLMLINLGLGSMIGTMAGITTPIIDTF-KV 491

  Fly   444 GQWQCSLLIAVVSFFIGLMYITPGGQYMLTLVDFFGASMIALVLGIAELYTIGWIYGTDRLCKDI 508
            .:...::...|.:|.:||:::...|.|.:|:.|.:.|::...::.|.|...:.|||||.:..:::
Human   492 PKEMFTVGCCVFAFLVGLLFVQRSGNYFVTMFDDYSATLPLTLIVILENIAVAWIYGTKKFMQEL 556

  Fly   509 EFMLGRKVGLYWRLCWSIITPLIMTVI----LIYFYATYQPLTYN----------NIVYPNWSYS 559
            ..|||.:...::...|..::||.|.|:    :|....|  |..|:          .:.:|||:.:
Human   557 TEMLGFRPYRFYFYMWKFVSPLCMAVLTTASIIQLGVT--PPGYSAWIKEEAAERYLYFPNWAMA 619

  Fly   560 IGWLITAFGILQLPIWMIVAIVR------DPGQTLGAKIR 593
            :  |||...:..||| .:|.::|      |...||....:
Human   620 L--LITLIVVATLPI-PVVFVLRHFHLLSDGSNTLSVSYK 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:444915	194/631 (31%)
SLC6A17	NP_001010898.1	SLC6sbd_NTT4	60..648	CDD:271403	192/621 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	680..727