DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15279 and GlyT

DIOPT Version :9

Sequence 1:	NP_609726.1	Gene:	CG15279 / 34863	FlyBaseID:	FBgn0028886	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_611836.2	Gene:	GlyT / 37772	FlyBaseID:	FBgn0034911	Length:	1188	Species:	Drosophila melanogaster

Alignment Length:	624	Identity:	227/624 - (36%)
Similarity:	339/624 - (54%)	Gaps:	53/624 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 AAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIVLFLIGKPIYYLE 107
            |.:...||.||....:||:|.:..|||||||||||:...:|||||||||:.|:|.:.|.|:.::|
  Fly    50 AGESEHERGTWTGRFDFLLSLLGYSVGLGNVWRFPYLCYNNGGGAFLIPFTIMLVIAGLPLMFME 114

  Fly   108 MVIGQFSSRGSVKVF-DLCPAMKGVGAGQAFQVFMLSTYYAALVAIIGRYFIESFRNPLPWSTCR 171
            :..||:::.|.|.|: ..||..:|:|.|......::..||..::|....|...||...|||..|.
  Fly   115 LSFGQYAALGPVAVYRRFCPLFRGLGTGMILVSAIVMLYYNLIIAWTIFYMFASFAPVLPWQNCE 179

  Fly   172 AEWGI-HCINSAPDASNWSQLESND-----QRPQNYTMKSQNDRVITS----------SEWYFVK 220
            ..|.. :|.:.|    ...|.|:.:     :...|.|..::|:  ||:          :|.||..
  Fly   180 PAWSTKYCFSYA----QADQCEATNGTYYLRTCHNATSAAENN--ITTLALGALKRPPAEEYFNN 238

  Fly   221 EVLHEKPNIEEGIGLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAV 285
            .||.....||| .|.....|...||:||:.||..:.:||:||||..||.||||||::.:|.||.|
  Fly   239 FVLGLSKGIEE-TGSIKLSLAACLFLAWTIVFLCLCKGVQSSGKVVYFTALFPYVVLVILFVRGV 302

  Fly   286 TLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVT 350
            ||||:..||.:::.|.|.::.:.:||..|..|.|::||..:|.:|..||:|||.:|.::|:.||.
  Fly   303 TLPGASTGILFYLTPDWKQLANAQVWGDAAVQIFFALSPAWGGLITLSSYNKFSNNCYKDSLIVA 367

  Fly   351 GLDTMTSLLAGFTIFGILGHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFL 415
            ..:..||..||..||.|:|.||||:.. |:..||..|||||||.||:.:.:....| :::||||:
  Fly   368 FCNIATSFFAGLVIFSIIGFLAHELNV-DVEKVVDQGAGLAFIVYPEVVTRLPVSP-VWAVLFFV 430

  Fly   416 MLFVLGIGSNIAMTSCSVTAIRDRFPNFGQWQ--CSLLIAVVSFFIGLMYITPGGQYMLTLVDFF 478
            ||..||:.|..|:.....|||.|||||..|::  ..|.:|:..:..||.:.|..|.|.|.|:|.:
  Fly   431 MLLTLGLDSQFALMETVTTAILDRFPNLRQYKIWVVLSVAIFGYIGGLGFTTNSGMYWLQLMDKY 495

  Fly   479 GASMIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKV---GLYWRLCWSIITPLIMTVILIYFY 540
            .|:...|::.|:|...|.||||:.|...||:.|:|::.   ..:|.:.|..|||..:..||.:.:
  Fly   496 AANWSVLLIAISECILIAWIYGSQRFLNDIQGMIGKRSWFWNFFWGIMWRYITPATLLFILFFNW 560

  Fly   541 ATYQPLTYNNIVYPNWSYSIGWLITAFGILQLPIWMIVA---IVRDP-GQTLGAKIRGAFTPKKN 601
            ..|:|..|.:.|||.|:.::||::   |:|.:.:..:||   |.|.| ..:...:|:....|...
  Fly   561 VEYKPAKYGHYVYPMWADAVGWIV---GLLPVLVIFLVAFQEIWRAPMSLSFRDRIKHLLQPTAE 622

  Fly   602 WGPSD----PLLREQYHKE-----------IENELTPKR 625
            |||:.    .|..|:|..:           ||.|.:||:
  Fly   623 WGPAGRPCVNLHAERYQSQNYDGVTNTKILIEEEASPKQ 661

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	213/573 (37%)
GlyT	NP_611836.2	SNF	57..603	CDD:249680	210/557 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920