Protein Alignment CG15279 and SLC6A19

DIOPT Version :9

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: NP_001003841.1
• Gene: SLC6A19 / 340024
• HGNCID: 27960
• Length: 634
• Species: Homo sapiens
• Alignment Length: 635
• Identity: 188/635 - (29%)
• Similarity: 312/635 - (49%)
• Gaps: 109/635 - (17%)

  Fly    32 PALRD-NSDDQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIV 95
            |:|.: .:.:||.|   ..|..|....:::::|:...||||||||||:....:|||||:||:||:
Human    16 PSLAELETIEQEEA---SSRPKWDNKAQYMLTCLGFCVGLGNVWRFPYLCQSHGGGAFMIPFLIL 77

  Fly    96 LFLIGKPIYYLEMVIGQFSSRGSVKVF-DLCPAMKGVGAGQAFQVFMLSTYYAALVAIIGRYFIE 159
            |.|.|.|:.|||..|||...|||:.|: .:.||:||:|.......||:..||..:::.|..|...
Human    78 LVLEGIPLLYLEFAIGQRLRRGSLGVWSSIHPALKGLGLASMLTSFMVGLYYNTIISWIMWYLFN 142

  Fly   160 SFRNPLPWSTCRAEWGIHCINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITSS--EWYFVKEV 222
            ||:.|||||.|                           |.|.......|....||  ::::.:|.
Human   143 SFQEPLPWSDC---------------------------PLNENQTGYVDECARSSPVDYFWYRET 180

  Fly   223 LHEKPNIEEGIGLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTL 287
            |:...:|.:. |...|.:::.|..|||.::....||::::|||.|..:..|||::.:.|:|.:||
Human   181 LNISTSISDS-GSIQWWMLLCLACAWSVLYMCTIRGIETTGKAVYITSTLPYVVLTIFLIRGLTL 244

  Fly   288 PGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGL 352
            .|:.:||.:...|...::..|..|..|..|.|:|.|:.||.:|.:||:|...:|..:|:.||:.:
Human   245 KGATNGIVFLFTPNVTELAQPDTWLDAGAQVFFSFSLAFGGLISFSSYNSVHNNCEKDSVIVSII 309

  Fly   353 DTMTSLLAGFTIFGILGHLAHEIGTD----DIGSVVKG--------------------------- 386
            :..||:.....::.::|..|.:...|    :|.:::.|
Human   310 NGFTSVYVAIVVYSVIGFRATQRYDDCFSTNILTLINGFDLPEGNVTQENFVDMQQRCNASDPAA 374

  Fly   387 --------------------GAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMTSC 431
                                |.|||||.:.:||.|.. |..::|||||:|||.||:.|.......
Human   375 YAQLVFQTCDINAFLSEAVEGTGLAFIVFTEAITKMP-LSPLWSVLFFIMLFCLGLSSMFGNMEG 438

  Fly   432 SVTAIRDRFPNFGQWQCSLLIAVV---SFFIGLMYITPGGQYMLTLVDFFGASMIALVLGIAELY 493
            .|..::|......:|...:|..::   :|.||.::....|||.|:|:|.:..|:..|::...|::
Human   439 VVVPLQDLRVIPPKWPKEVLTGLICLGTFLIGFIFTLNSGQYWLSLLDSYAGSIPLLIIAFCEMF 503

  Fly   494 TIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVILIYFYA--TYQPLTYN------- 549
            ::.::||.||..||||||:|.|..::|::.|.:::||:|.:|.::|:.  ..|.|||:
Human   504 SVVYVYGVDRFNKDIEFMIGHKPNIFWQVTWRVVSPLLMLIIFLFFFVVEVSQELTYSIWDPGYE 568

  Fly   550 ------NIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRD----PGQTLG 589
                  .|.||||.|.:..::.....|.:|.:.|..::|:    ||...|
Human   569 EFPKSQKISYPNWVYVVVVIVAGVPSLTIPGYAIYKLIRNHCQKPGDHQG 618

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	183/616 (30%)
SLC6A19	NP_001003841.1	SLC5-6-like_sbd	32..612	CDD:294310	180/608 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810