Protein Alignment CG15279 and SLC6A16

DIOPT Version :9

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_011525161.2
• Gene: SLC6A16 / 28968
• HGNCID: 13622
• Length: 781
• Species: Homo sapiens
• Alignment Length: 671
• Identity: 152/671 - (22%)
• Similarity: 269/671 - (40%)
• Gaps: 172/671 - (25%)

  Fly    40 DQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIVLFLIGKPIY 104
            :::.::|...|..|....|::::.:..|:....:|||.:..|::||.:|...|:.:|||:|.|:.
Human   175 EKKESEVLLARPFWSSKTEYILAQVGFSMKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLL 239

  Fly   105 YLEMVIGQFSSRGSVKVFD-LCPAMKGVGAGQAFQVFMLSTYYAALVAIIGRYFIESFRNPLPWS 168
            :|||..||...:|.:.|:. :.|.:.|||.......|:|..|:..:.:.|..|..:||:.|:||.
Human   240 FLEMAAGQSMRQGGMGVWKIIAPWIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWE 304

  Fly   169 TCRAEWGIHCINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGI 233
            .|            |...|.|..:...:|             .|.|.:::.::.|.....||:|
Human   305 KC------------PLTMNSSGFDPECER-------------TTPSIYFWYQQALKASDRIEDG- 343

  Fly   234 GLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFI 298
            |.|.:.||:..|:.|..|...:..|:||:||.|
Human   344 GSPVYSLVLPFFLCWCLVGAFMINGLKSTGKIS-------------------------------- 376

  Fly   299 KPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFT 363
                 .:.:..||..|..|...:..:..|::...:|:....:|...||.:|:.::.:|.|:  ||
Human   377 -----DVYNMSVWSLAGGQVLSNTGIGLGSVASLASYMPQSNNCLSDAFLVSVINLLTLLV--FT 434

  Fly   364 IFG--ILG-------HLAHEIGTDDIGSVVKGG------------------------AGL----- 390
            .|.  :||       |...|...:.:..::..|                        :||
Human   435 SFNFCVLGFWATVITHRCCERNAEILLKLINLGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIK 499

  Fly   391 -------------------------AFISYPDAIAKFKNLPQIF-SVLFFLMLFVLGIGSNIAMT 429
                                     ||:|:.:|::...  |.:| |.:|||||..:|:.|.|.:.
Human   500 SMVLREVTECNIETQFLKASEGPKFAFLSFVEAMSFLP--PSVFWSFIFFLMLLAMGLSSAIGIM 562

  Fly   430 SCSVTAIRDRFPNFGQWQCSLLIAV--VSFFIGLMYITPGGQYMLTLVDFFGASMIALVLGIAEL 492
            ...:|.::|.|..|.:....|::.|  :.|..||.:..|.|.|.:.|:..:......:|:.:.|.
Human   563 QGIITPLQDTFSFFRKHTKLLIVGVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFET 627

  Fly   493 YTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVILI--YFYATYQPLTY------- 548
            ..:.|.||..|...|:..:||..:...:...|..:.|:::.:|.:  ..:...:|:||
Human   628 MAVSWAYGARRFLADLTILLGHPISPIFGWLWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSST 692

  Fly   549 -NNIV--YPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQTLGAKI-RGAFTPKKNWGP----- 604
             ..::  ||.|:..:  :||.|.|:.|||         |...:..:| |..|.||...||
Human   693 SKEVLRPYPPWALLL--MITLFAIVILPI---------PAYFVYCRIHRIPFRPKSGDGPMTAST 746

  Fly   605 SDPLLREQYHKEIENELTPKR 625
            |.||         .::|||.:
Human   747 SLPL---------SHQLTPSK 758

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	141/627 (22%)
SLC6A16	XP_011525161.2	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820