DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15279 and Slc6a13

DIOPT Version :9

Sequence 1:	NP_609726.1	Gene:	CG15279 / 34863	FlyBaseID:	FBgn0028886	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	NP_001366036.1	Gene:	Slc6a13 / 14412	MGIID:	95629	Length:	602	Species:	Mus musculus

Alignment Length:	610	Identity:	212/610 - (34%)
Similarity:	321/610 - (52%)	Gaps:	50/610 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 TASTVEISTNSPALRDNSDDQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGG 85
            |.|..|.....||:....:|...     ||..|...:||::|.....:|||||||||:....|||
Mouse     8 TTSNGETKPVCPAMEKVEEDGTL-----EREHWNNKMEFVLSVAGEIIGLGNVWRFPYLCYKNGG 67

  Fly    86 GAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVF-DLCPAMKGVGAGQAFQVFMLSTYYAAL 149
            |||.|||||.||..|.|:::||..:||::::|.:..: .:||..:|:|......|.:|:.||..:
Mouse    68 GAFFIPYLIFLFTCGIPVFFLETALGQYTNQGGITAWRRICPIFEGIGYASQMIVSLLNVYYIVV 132

  Fly   150 VAIIGRYFIESFRNPLPWSTCRAEWGI-HCINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITS 213
            :|....|...||...|||.:|..||.. :|:...         ::||.  .|.|.::....||.
Mouse   133 LAWALFYLFSSFTTDLPWGSCSHEWNTENCVEFQ---------KANDS--MNVTSENATSPVIE- 185

  Fly   214 SEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMG 278
               ::.:.||.....|:. :|...||||:.|.:||...:|.|.:||||:||..||.|.|||:::.
Mouse   186 ---FWERRVLKLSDGIQH-LGSLRWELVLCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYLMLV 246

  Fly   279 VLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVH 343
            |||:|.|||||:..||.:::.|...::.||:||..|.||.|:|.::|.|.:....|:||:.:|.:
Mouse   247 VLLIRGVTLPGAAQGIQFYLYPNITRLWDPQVWMDAGTQIFFSFAICLGCLTALGSYNKYHNNCY 311

  Fly   344 RDAAIVTGLDTMTSLLAGFTIFGILGHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQI 408
            ||...:..|::.||.:|||.||.|||.::.|.|. .|..|.:.|.|||||:||.|:......| :
Mouse   312 RDCIALCILNSSTSFMAGFAIFSILGFMSQEQGV-PISEVAESGPGLAFIAYPRAVVMLPFSP-L 374

  Fly   409 FSVLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPNFGQWQ-----CSLLIAVVSFFIGLMYITPGG 468
            ::..||.|:.:||:.|........|||:.|.:|...:.:     ..|:::|:||||||:.:|.||
Mouse   375 WACCFFFMVVLLGLDSQFVCVESLVTALVDMYPRVFRKKNRREVLILIVSVISFFIGLIMLTEGG 439

  Fly   469 QYMLTLVDFFGAS-MIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIM 532
            .|:..|.|::.|| |..|.:.|.|...:.|:||..|...:||.|:|.|.....:.||...||.:.
Mouse   440 MYVFQLFDYYAASGMCLLFVAIFESLCVAWVYGAGRFYDNIEDMIGYKPWPLIKYCWLFFTPAVC 504

  Fly   533 TVILIYFYATYQPLTYN-NIVYPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQTLGAKIRGAF 596
            ....::....|.||||| ...||.|..::|||:....::.:|.|.|..:     :||...:|...
Mouse   505 LATFLFSLIKYTPLTYNKKYTYPWWGDALGWLLALSSMICIPAWSIYKL-----RTLKGPLRERL 564

  Fly   597 ---------TPKKN----WGPSDPL 608
                     .|:||    ..|:.|:
Mouse   565 RQLVCPAEDLPQKNQPEPTAPATPM 589

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	200/565 (35%)
Slc6a13	NP_001366036.1	SLC5-6-like_sbd	32..575	CDD:382020	200/565 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820