Protein Alignment CG15279 and Slc6a5

DIOPT Version :9

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_006540608.1
• Gene: Slc6a5 / 104245
• MGIID: 105090
• Length: 831
• Species: Mus musculus
• Alignment Length: 649
• Identity: 231/649 - (35%)
• Similarity: 361/649 - (55%)
• Gaps: 62/649 - (9%)

  Fly     9 QNLAFVGDDGRSTASTVEISTNSPALRDNSDDQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNV 73
            |:...:|.||.::.....::|.:....:..|:.:|      |..|...::|::|.:..:||||||
Mouse   190 QSTVVLGTDGIASVLPGSVATTTIPEDEQGDENKA------RGNWSSKLDFILSMVGYAVGLGNV 248

  Fly    74 WRFPFTALDNGGGAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVFDLCPAMKGVGAGQAFQ 138
            ||||:.|..|||||||||||::|.|.|.||::||:.:|||:|:|.|.|:...||::|.|......
Mouse   249 WRFPYLAFQNGGGAFLIPYLMMLALAGLPIFFLEVSLGQFASQGPVSVWKAIPALQGCGIAMLII 313

  Fly   139 VFMLSTYYAALVAIIGRYFIESFRNPLPWSTCRAEW------------------GIH-------- 177
            ..:::.||..::.....|...||.:.|||.:|...|                  |.|
Mouse   314 SVLIAIYYNVIICYTLFYLFASFVSVLPWGSCNNPWNTPECKDKTKLLLDSCVIGDHPKIQIKNS 378

  Fly   178 --CINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITSSEWYFVKEVLHEKPNIEEGIGLP---N 237
              |:.:.|:.:           ..|:|.:: |...::.||.||...||    .|..||..|   .
Mouse   379 TFCMTAYPNLT-----------MVNFTSQT-NKTFVSGSEEYFKYFVL----KISAGIEYPGEIR 427

  Fly   238 WELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQW 302
            |.|...||:||..|:..:.:|:|||||..||.|.||||::.:||:|.|||||:..||:|||.|:|
Mouse   428 WPLAFCLFLAWVIVYASLAKGIKSSGKVVYFTATFPYVVLVILLIRGVTLPGAGAGIWYFITPKW 492

  Fly   303 GKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGI 367
            .|:.|..||..|.||.|:|||..:|.:|..||:|||.:|.:||..|||..::.||:.|||.||.:
Mouse   493 EKLTDATVWKDAATQIFFSLSAAWGGLITLSSYNKFHNNCYRDTLIVTCTNSATSIFAGFVIFSV 557

  Fly   368 LGHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMTSCS 432
            :|.:|:|... :|.:|...|.|:||:.||:|:.:.. |...::::|||||..||:.:..|.....
Mouse   558 IGFMANERKV-NIENVADQGPGIAFVVYPEALTRLP-LSPFWAIIFFLMLLTLGLDTMFATIETI 620

  Fly   433 VTAIRDRFPNFGQWQ---CSLLIAVVSFFIGLMYITPGGQYMLTLVDFFGASMIALVLGIAELYT 494
            ||:|.|.||.:.:..   .:|...:..|.:|...||.||.||..|||.:.||...:::.|.||..
Mouse   621 VTSISDEFPKYLRTHKPVFTLGCCICFFIMGFPMITQGGIYMFQLVDTYAASYALVIIAIFELVG 685

  Fly   495 IGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVILIYFYATYQPLTYNNIVYPNWSYS 559
            |.::||..|.|:|||.|:|.|..::|::||:.:||.|:|.||.:.:..::|:||.:..|||||..
Mouse   686 ISYVYGLQRFCEDIEMMIGFKPNIFWKVCWAFVTPTILTFILCFSFYQWEPMTYGSYRYPNWSMV 750

  Fly   560 IGWLITAFGILQLPIWMIVAIVRDPGQTLGAKIRGAFTPKKNWGPSDPLLREQYHKEIENELTP 623
            :|||:.|..::.:||..::.:...||:.: .:::...:|:.:||   |.|.:...:..:|.:.|
Mouse   751 LGWLMLACSVIWIPIMFVIKMYLAPGRFI-ERLKLVCSPQPDWG---PFLAQHRGERYKNMIDP 810

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	217/581 (37%)
Slc6a5	XP_006540608.1	SLC6sbd_GlyT2	225..821	CDD:271389	224/608 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11616
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020