Protein Alignment CG15279 and slc6a12

DIOPT Version :10

• Sequence 1: NP_609726.1
• Gene: CG15279 / 34863
• FlyBaseID: FBgn0028886
• Length: 639
• Species: Drosophila melanogaster
• Sequence 2: XP_031754510.1
• Gene: slc6a12 / 100492029
• XenbaseID: XB-GENE-6033368
• Length: 612
• Species: Xenopus tropicalis
• Alignment Length: 583
• Identity: 217/583 - (37%)
• Similarity: 331/583 - (56%)
• Gaps: 34/583 - (5%)

  Fly    48 EERATWGKGVEFLMSCIAMSVGLGNVWRFPFTALDNGGGAFLIPYLIVLFLIGKPIYYLEMVIGQ 112
            |:|..|...|||::|.....:|||||||||:....||||||.|||||.||..|.|:::||..:||
 Frog    33 EDRGQWSNKVEFVLSVAGEIIGLGNVWRFPYLCYKNGGGAFFIPYLIFLFTCGIPVFFLETALGQ 97

  Fly   113 FSSRGSVKVF-DLCPAMKGVG-AGQAFQVFMLSTYYAALVAIIGRYFIESFRNPLPWSTCRAEWG 175
            ::|:|.:..: .:||..:|:| |.|..:.: |:.||..::|....|...||...|||:||...|.
 Frog    98 YTSQGGITAWRKICPLFEGIGYASQVIEGY-LNIYYIVILAWALFYLFSSFTAELPWATCNNTWN 161

  Fly   176 I-HCINSAPDASNWSQLESNDQRPQNYTMKSQNDRVITSS-EWYFVKEVLHEKPNIEEGIGLPNW 238
            . |||:....:.|::.||::                 ||| ..::.:.|||....||. :|...|
 Frog   162 TEHCIDFVGKSENFTSLENS-----------------TSSVVEFWERRVLHLSEGIEH-LGNVRW 208

  Fly   239 ELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFPYVIMGVLLVRAVTLPGSIDGIYYFIKPQWG 303
            :|.:.|.:||...:|.|.:||||:||..||.|.||||::.:||||.|||||:.:||.:::||...
 Frog   209 DLALCLLLAWIICYFCIWKGVKSTGKVVYFTATFPYVMLIILLVRGVTLPGAYEGIIFYLKPDMT 273

  Fly   304 KILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKFGHNVHRDAAIVTGLDTMTSLLAGFTIFGIL 368
            ::.||:||..|.||.|:|.::|.|.:....|:||:.:|.:||...:..|:::||.:|||.||.:|
 Frog   274 RLQDPQVWMDAGTQIFFSYAICQGCLTALGSYNKYNNNCYRDCIALCFLNSITSFVAGFAIFSVL 338

  Fly   369 GHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFKNLPQIFSVLFFLMLFVLGIGSNIAMTSCSV 433
            |.:|.|.|. .|..|.:.|.|||||:||.|:......| ::|.||||||..||:.|........|
 Frog   339 GFMAQEQGV-PISEVAESGPGLAFIAYPKAVTMMPVSP-LWSCLFFLMLIFLGLDSQFVCVESLV 401

  Fly   434 TAIRDRFPN-----FGQWQCSLLIAVVSFFIGLMYITPGGQYMLTLVDFFGASMIALV-LGIAEL 492
            |||.|.||:     :.:....|.:||:.:.:||:.:|.||.|:..|.|::.||...|: :.|.|:
 Frog   402 TAIVDMFPHVFRKKYRREFFILAVAVICYLLGLILLTEGGMYVFQLFDYYAASGTCLLFVAIFEV 466

  Fly   493 YTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSIITPLIMTVILIYFYATYQPLTYNN-IVYPNW 556
            ..:|::||.:|...:||.|:|.:.....:.||...||.:.....::....|.||.||| .|||:|
 Frog   467 ICVGYVYGANRFYDNIEDMIGYRPWPLVKYCWLFATPAVCLGTFLFSLIKYSPLKYNNRYVYPSW 531

  Fly   557 SYSIGWLITAFGILQLPIWMIVAIVRDPGQTLGAKIRGAFTPKKNWGPSDPLLREQYH-KEIE 618
            .|:||||:....::.:||:....|:|..| :...:::...||..:.......|:::.. |:||
 Frog   532 GYAIGWLMALSSMICIPIYAFYIILRTKG-SFTQRLKQLVTPHTDLPQPKKYLKDRADPKQIE 593

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:444915	210/558 (38%)
slc6a12	XP_031754510.1	SLC5-6-like_sbd	34..572	CDD:444915	210/559 (38%)