DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15279 and slc6a11b

DIOPT Version :9

Sequence 1:	NP_609726.1	Gene:	CG15279 / 34863	FlyBaseID:	FBgn0028886	Length:	639	Species:	Drosophila melanogaster
Sequence 2:	XP_017213744.2	Gene:	slc6a11b / 100150472	ZFINID:	ZDB-GENE-121116-2	Length:	617	Species:	Danio rerio

Alignment Length:	592	Identity:	215/592 - (36%)
Similarity:	327/592 - (55%)	Gaps:	36/592 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 DGRSTASTVEISTNSPALRDNSDDQEAAKVPEERATWGKGVEFLMSCIAMSVGLGNVWRFPFTAL 81
            :|::..|....|.|..|:|.|.     .||..||..|...|||::|.....:|||||||||:...
Zfish    11 NGKAEESMDPESANPSAVRSND-----KKVVNERGQWNNKVEFVLSVAGEIIGLGNVWRFPYLCY 70

  Fly    82 DNGGGAFLIPYLIVLFLIGKPIYYLEMVIGQFSSRGSVKVF-DLCPAMKGVG-AGQAFQVFMLST 144
            .||||||.:||:|.....|.|:::||..:|||:|.|.:..: .:||..:|:| |.|..:.. |:.
Zfish    71 KNGGGAFFVPYVIFFVCCGIPVFFLETALGQFTSEGGITCWRKVCPLFEGIGYATQVIEAH-LNV 134

  Fly   145 YYAALVAIIGRYFIESFRNPLPWSTCRAEWGI-HCINSAPDASNWSQLESNDQRPQNYTMKSQND 208
            ||..::|....|....|...|||::|...|.. :|:            :.|::...|:|......
Zfish   135 YYVVILAWAIFYLFNCFTTELPWASCGHYWNTENCV------------DFNNESIANFTNPYSTS 187

  Fly   209 RVITSSEWYFVKEVLHEKPNIEEGIGLPNWELVIGLFIAWSCVFFIIRRGVKSSGKASYFLALFP 273
            .|:.    ::.:.||.....|||..|| .|||.:.|.|||...:|.|.:|.||:||..|..|.||
Zfish   188 PVME----FWERRVLKISSGIEEVGGL-RWELALCLAIAWVICYFCIWKGPKSTGKVVYVTATFP 247

  Fly   274 YVIMGVLLVRAVTLPGSIDGIYYFIKPQWGKILDPKVWYAAVTQCFYSLSVCFGNIIMYSSFNKF 338
            |.::.:||:|.:||||:.:||.:::.|...::.||:||..|.||.|:|.::|.|.:....|:|.:
Zfish   248 YFMLLILLLRGITLPGAANGIKFYLYPDISRLSDPQVWVDAGTQIFFSYAICLGCLTALGSYNSY 312

  Fly   339 GHNVHRDAAIVTGLDTMTSLLAGFTIFGILGHLAHEIGTDDIGSVVKGGAGLAFISYPDAIAKFK 403
            .:|.:||..::..|::.||.:|||.||.:||.:|:|... .|.:|.:.|.|||||:||.|:....
Zfish   313 NNNCYRDCLMLCCLNSGTSFVAGFAIFSVLGFMAYEQNV-PIEAVAESGPGLAFIAYPKAVTMMP 376

  Fly   404 NLPQIFSVLFFLMLFVLGIGSNIAMTSCSVTAIRDRFPNFGQ--WQCSLLI---AVVSFFIGLMY 463
            ..| :::.|||:||..||:.|........||||.|.:|...:  ::..|||   ::.|||:||:.
Zfish   377 WAP-LWAALFFMMLIFLGLDSQFVCVESLVTAIVDMYPKTFRVGYRRELLILGMSIASFFLGLIM 440

  Fly   464 ITPGGQYMLTLVDFFGAS-MIALVLGIAELYTIGWIYGTDRLCKDIEFMLGRKVGLYWRLCWSII 527
            :|.||.|:..|.|.:.|| |..|.:.|.|...|||:||:||...:||.|:|.|...:.:.||...
Zfish   441 LTEGGMYVFQLFDSYAASGMCLLFVAIFESICIGWVYGSDRFYLNIEDMIGYKPIFFIKWCWKFF 505

  Fly   528 TPLIMTVILIYFYATYQPLTYNNI-VYPNWSYSIGWLITAFGILQLPIWMIVAIVRDPGQTLGAK 591
            ||.|.|.|.::|...|:||.|||: .||:|.|.|||::....::.:|:.::..|.:..| |...:
Zfish   506 TPGICTGIFLFFLIKYKPLKYNNVYTYPDWGYGIGWMMAMSSMVCIPLGILFQIWKTKG-TFRER 569

  Fly   592 IRGAFTP 598
            |:...||
Zfish   570 IKKLTTP 576

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15279	NP_609726.1	SLC5-6-like_sbd	50..598	CDD:294310	203/557 (36%)
slc6a11b	XP_017213744.2	SLC5-6-like_sbd	38..576	CDD:320982	204/558 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.920