Protein Alignment CG4650 and F10

DIOPT Version :10

• Sequence 1: NP_609722.2
• Gene: CG4650 / 34859
• FlyBaseID: FBgn0032549
• Length: 299
• Species: Drosophila melanogaster
• Sequence 2: NP_000495.1
• Gene: F10 / 2159
• HGNCID: 3528
• Length: 488
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 68/270 - (25%)
• Similarity: 111/270 - (41%)
• Gaps: 42/270 - (15%)

  Fly    14 LLPVPGSSQYLDGRCGLLTNGKIANNISSPWMAYLHTSELLYVCGGTVITEKLVLTAAHCTRASE 78
            |..:.|..:..||.|              ||.|.|...|....||||:::|..:||||||...::
Human   232 LTRIVGGQECKDGEC--------------PWQALLINEENEGFCGGTILSEFYILTAAHCLYQAK 282

  Fly    79 QLVARIGEFIGTDDANDTMLSEYQVSQTFIHSLYNTTTSANDIAILGLATDIVFSKTIRPICIVW 143
            :...|:|:.....:.....:.|.:|  ...|:.:...|...|||:|.|.|.|.|...:.|.|:..
Human   283 RFKVRVGDRNTEQEEGGEAVHEVEV--VIKHNRFTKETYDFDIAVLRLKTPITFRMNVAPACLPE 345

  Fly   144 --WTIWRKYIDNIQVLSGAQWGLPNDR-NESDAFRITDIRRQPANMCSTLNGTAILSSQFCAGDS 205
              |...........::||  :|..::: .:|...::.::.....|.|...:...|..:.|||| .
Human   346 RDWAESTLMTQKTGIVSG--FGRTHEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNMFCAG-Y 407

  Fly   206 DSK---LCNVDFSSPLGAIITFKNIQRYVLIGIATTNQKCKRA---SVYTDVLSHTDFILSVWRQ 264
            |:|   .|..|...|  .:..||:  .|.:.||.:..:.|.|.   .:||.|.:...:|
Human   408 DTKQEDACQGDSGGP--HVTRFKD--TYFVTGIVSWGEGCARKGKYGIYTKVTAFLKWI------ 462

  Fly   265 YRNGEKSPKT 274
                ::|.||
Human   463 ----DRSMKT 468

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4650	NP_609722.2	Tryp_SPc	33..258	CDD:214473	59/233 (25%)
F10	NP_000495.1	GLA	25..85	CDD:214503
		EGF_CA	86..122	CDD:238011
		FXa_inhibition	129..164	CDD:464251
		O-glycosylated at one site	183..203
		Tryp_SPc	235..464	CDD:238113	64/261 (25%)
		O-glycosylated at one site	476..485