Protein Alignment CSN1a and PSMD6

DIOPT Version :10

• Sequence 1: NP_609720.1
• Gene: CSN1a / 34857
• FlyBaseID: FBgn0028838
• Length: 364
• Species: Drosophila melanogaster
• Sequence 2: NP_001258708.1
• Gene: PSMD6 / 9861
• HGNCID: 9564
• Length: 442
• Species: Homo sapiens
• Alignment Length: 332
• Identity: 74/332 - (22%)
• Similarity: 116/332 - (34%)
• Gaps: 89/332 - (26%)

  Fly    22 PRLIRLKFIAQVCPELSVLALELALNHVKTTYNVKLYDELYKTLCVEVDRKYPNQ-SKGNEELHT 85
            |..|||.|           |..:...|...:|....|:.|.|:|..::|....|: .|.||:
Human    82 PTSIRLCF-----------AKPIIKRHRMPSYMAPYYEALCKSLDWQIDVDLLNKMKKANED--- 132

  Fly    86 TGGSEPSTSSGRGRVVVPYDSYWVEDNIMEATLMLQELDAELNFKKSNSGSSYVR-------RIL 143
                                             .|:.||.||...:.|.|.|.:|       ..|
Human   133 ---------------------------------ELKRLDEELEDAEKNLGESEIRDAMMAKAEYL 164

  Fly   144 EEIGDHHEKSGNLQMAVKFYARARPYCTSSENVINMFRNLIRVSI-YMENWWHVLT-YIDEAKQY 206
            ..|||   |.|.|....|.|.:.    .:..:.:::...|:|:.: ||:|  .::| ..::||
Human   165 CRIGD---KEGALTAFRKTYDKT----VALGHRLDIVFYLLRIGLFYMDN--DLITRNTEKAK-- 218

  Fly   207 AYGFENLAQE-----VPARLSCVAGLAHLGLKIYKSAAQYFLS-----TPYGRYDYDKIVAPEDV 261
                 :|.:|     ...||....||..:.::.:|.||:.||.     |.|...||...|.   .
Human   219 -----SLIEEGGDWDRRNRLKVYQGLYCVAIRDFKQAAELFLDTVSTFTSYELMDYKTFVT---Y 275

  Fly   262 TLYAGLCALATFDRETLQLNAINSEAFKPFFQLSPKMWTILAKFYAGEFDACMTLLREIENHVRL 326
            |:|..:.||   :|..|:...|............|.:...|...|...:......|..:|..::.
Human   276 TVYVSMIAL---ERPDLREKVIKGAEILEVLHSLPAVRQYLFSLYECRYSVFFQSLAVVEQEMKK 337

  Fly   327 DVYLSPH 333
            |...:||
Human   338 DWLFAPH 344

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CSN1a	NP_609720.1	RPN7	105..279	CDD:431387	47/192 (24%)
PSMD6	NP_001258708.1	RPN7	103..435	CDD:227514	66/300 (22%)