DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN1a and PCI8

DIOPT Version :9

Sequence 1:	NP_609720.1	Gene:	CSN1a / 34857	FlyBaseID:	FBgn0028838	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	NP_085069.3	Gene:	PCI8 / 854739	SGDID:	S000001333	Length:	444	Species:	Saccharomyces cerevisiae

Alignment Length:	200	Identity:	49/200 - (24%)
Similarity:	70/200 - (35%)	Gaps:	68/200 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 MLHLPSYADRYTDIPRLIRLKFIAQVCPELSVLALELALNHVKTTYN--VKLYDELYKTLCVEVD 70
            ::.:|  .|.|.|...|..||...|:.| |.|..|||.:|   |.:|  .|::......:|:
Yeast   233 LISIP--LDNYDDFIYLSDLKQFFQMTP-LLVNCLELLIN---TNFNKFFKIWHGEINKICM--- 288

  Fly    71 RKYPNQSKGNEELHTTGGSEPSTSSGRGRVVVPYDSYW---------------------VEDNIM 114
                      |.|..    |||.||. ..|::....|:                     :||...
Yeast   289 ----------ESLFL----EPSWSSS-AAVIMRCKIYFFYLRISKKLQFSYLSSTLGIDLEDIKE 338

  Fly   115 EATLMLQELDAELNFKKSNSGSSYVRRILEEIGD--HHEKSGNLQMAVKFYARARPYCTSSENVI 177
            |.|.::  :..:|||              |..||  |.|.|..||..|...:|..   |....||
Yeast   339 ELTKLI--ISGQLNF--------------EIDGDVIHFEDSSILQSIVNEISRNG---TMINEVI 384

  Fly   178 NMFRN 182
            :..:|
Yeast   385 DKLKN 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN1a	NP_609720.1	RPN7	105..281	CDD:287560	21/100 (21%)
PCI8	NP_085069.3	PINT	296..387	CDD:214509	25/110 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930