DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CSN1a and gps1

DIOPT Version :9

Sequence 1:	NP_609720.1	Gene:	CSN1a / 34857	FlyBaseID:	FBgn0028838	Length:	364	Species:	Drosophila melanogaster
Sequence 2:	XP_021327265.1	Gene:	gps1 / 777711	ZFINID:	ZDB-GENE-041111-240	Length:	527	Species:	Danio rerio

Alignment Length:	348	Identity:	138/348 - (39%)
Similarity:	211/348 - (60%)	Gaps:	21/348 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 EETMLHLPSYADRYTDIPRLIRLKFIAQVCPELSVLALELALNHVKTTYNVKLYDELYKTLCVEV 69
            |...|.|..||..|:.:.|:.||:|||..||:|.|.||::||:.|:.|:||.:|:|:::.| .|.
Zfish    78 ENPTLDLEQYASSYSGLMRIERLQFIADHCPQLRVEALKMALSFVQRTFNVDVYEEIHRKL-TEA 141

  Fly    70 DRKYPNQSKGNEELHTTGGSEPSTSSGRGRVVVPYDSYWVEDNIMEATLMLQELDAELNFKKSNS 134
            .|    :.:|..:....|..||.          |.|:.|.|....:|.|.|::||.:|...|.||
Zfish   142 TR----EVQGVPDAVPEGAVEPP----------PLDTAWAESTRKKALLKLEKLDTDLKNYKGNS 192

  Fly   135 GSSYVRRILEEIGDHHEKSGNLQMAVKFYARARPYCTSSENVINMFRNLIRVSIYMENWWHVLTY 199
            ....:||..:::|||:...|:|..|:|.|:|||.||||:::||||..|:|:||:|::||.|||:|
Zfish   193 IKESIRRGHDDLGDHYLDCGDLSNALKCYSRARDYCTSAKHVINMCLNVIKVSVYLQNWSHVLSY 257

  Fly   200 IDEAKQYAYGFENLA------QEVPARLSCVAGLAHLGLKIYKSAAQYFLSTPYGRYDYDKIVAP 258
            :.:|:......|...      |.|..:|.|.||||.|..:.||.||:.||...:...|:.::::|
Zfish   258 VSKAESTPEIAEQRGERDSQNQAVLTKLKCAAGLAELASRKYKPAAKCFLQASFDHCDFPELLSP 322

  Fly   259 EDVTLYAGLCALATFDRETLQLNAINSEAFKPFFQLSPKMWTILAKFYAGEFDACMTLLREIENH 323
            .:|.:|.||||||||||:.||.|.|:|.:||.|.:|.|::..|:.|||..::.:|:.:|.|::::
Zfish   323 SNVAVYGGLCALATFDRQELQRNVISSSSFKLFLELEPQVRDIIFKFYESKYASCLKMLDEMKDN 387

  Fly   324 VRLDVYLSPHVSALYDLIMARML 346
            :.||:||:|||..||..|..|.|
Zfish   388 LLLDMYLAPHVRTLYTQIRNRAL 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CSN1a	NP_609720.1	RPN7	105..281	CDD:287560	77/181 (43%)
gps1	XP_021327265.1	RPN7	163..345	CDD:313757	77/181 (43%)
gps1	XP_021327265.1	PCI	360..464	CDD:307522	20/51 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D223526at33208
OrthoFinder	1	1.000	-	-		FOG0005242
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14145
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020