Protein Alignment osp and CYTH3

DIOPT Version :9

• Sequence 1: NP_001162975.1
• Gene: osp / 34850
• FlyBaseID: FBgn0003016
• Length: 1566
• Species: Drosophila melanogaster
• Sequence 2: NP_004218.1
• Gene: CYTH3 / 9265
• HGNCID: 9504
• Length: 399
• Species: Homo sapiens
• Alignment Length: 432
• Identity: 80/432 - (18%)
• Similarity: 141/432 - (32%)
• Gaps: 157/432 - (36%)

  Fly   274 EEDDGVETG---EDVD-EDEEDETSVPRKSKTVSMGGQDENNRNAGNEITNRVSQPTTCLLIEDI 334
            :||.|.|.|   ||:. |:.|:...:.|:.|.                            ||:||
Human     2 DEDGGGEGGGVPEDLSLEEREELLDIRRRKKE----------------------------LIDDI 38

  Fly   335 RRDEKTIKDIANTITNLSQ-------QQNKRWS-------------------------------- 360
            .|.:..|.::...|.||:.       |:||:.:
Human    39 ERLKYEIAEVMTEIDNLTSVEESKTTQRNKQIAMGRKKFNMDPKKGIQFLIENDLLQSSPEDVAQ 103

  Fly   361 ----------TAVNNALNNQ--------------HHFGHHSQYQVTSR-----------DETDFQ 390
                      |.:.:.|..:              |.|...:..|...:           .:.|..
Human   104 FLYKGEGLNKTVIGDYLGERDEFNIKVLQAFVELHEFADLNLVQALRQFLWSFRLPGEAQKIDRM 168

  Fly   391 MSSNSSSTKSQNPASERPKSLPLASNSTPAIVS-AIVKKIPTVMEQGDKTKPTARLQLHLKSPKH 454
            |.:.:|.....||.       ...|..|..::| ||:....::.....:.||||.        :.
Human   169 MEAFASRYCLCNPG-------VFQSTDTCYVLSFAIIMLNTSLHNHNVRDKPTAE--------RF 218

  Fly   455 YQHERGDPDGGCNLDELCVN-YMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDN 518
            ....||..:||...:||..| |.:..:|...:.:.:....:.....|.:|       |||:|...
Human   219 IAMNRGINEGGDLPEELLRNLYESIKNEPFKIPEDDGNDLTHTFFNPDRE-------GWLLKLGG 276

  Fly   519 RTCEWSKHWFTLSGAALFYYRDPLCEE-RGVLDGVLDVNSLTSVIPEPAASKQHAFQL------- 575
            |...|.:.||.|:...|:|:.....:| ||::.  |:..|:..| .:|  .|.:.|:|
Human   277 RVKTWKRRWFILTDNCLYYFEYTTDKEPRGIIP--LENLSIREV-EDP--RKPNCFELYNPSHKG 336

  Fly   576 ------TTWDKQRLV--------LASLSPSSRNSWLAVLRSA 603
                  .|....|:|        :::.||..:..|:..::::
Human   337 QVIKACKTEADGRVVEGNHVVYRISAPSPEEKEEWMKSIKAS 378

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	27/117 (23%)
		PH	509..603	CDD:278594	27/115 (23%)
		SbcC	726..1353	CDD:223496
CYTH3	NP_004218.1	Sec7	66..248	CDD:396096	30/196 (15%)
		PH_GRP1-like	263..382	CDD:269954	29/128 (23%)
		C-terminal autoinhibitory region. /evidence=ECO:0000269|PubMed:23940353	391..399

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910