Protein Alignment osp and PLEKHA1

DIOPT Version :9

• Sequence 1: NP_001162975.1
• Gene: osp / 34850
• FlyBaseID: FBgn0003016
• Length: 1566
• Species: Drosophila melanogaster
• Sequence 2: XP_011538319.1
• Gene: PLEKHA1 / 59338
• HGNCID: 14335
• Length: 416
• Species: Homo sapiens
• Alignment Length: 475
• Identity: 88/475 - (18%)
• Similarity: 141/475 - (29%)
• Gaps: 164/475 - (34%)

  Fly   406 ERPKSLPLASNSTPAIVSAIVKKIP---------------------------------------- 430
            :.|::||..|:...||....:.|:.
Human    44 DNPQNLPSGSSRVGAIKLTYISKVSDATKLRPKAEFCFVMNAGMRKYFLQANDQQDLVEWVNVLN 108

  Fly   431 -----TVMEQGDKTKPTARLQLHLKSPKHYQHERGDPDGGCNLDELCVNYMAKTDEL-RSVGKAN 489
                 ||.:|.|....:..|..|.:..|.....|.|..||..:  :......:.:|. .|:.:.|
Human   109 KAIKITVPKQSDSQPNSDNLSRHGECGKKQVSYRTDIVGGVPI--ITPTQKEEVNECGESIDRNN 171

  Fly   490 SKSSSGQ-----GKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPLCEERGVL 549
            .|.|...     .|||  ::|...|.|:.:||......|.:.:|.|....:.|::..|.:|...:
Human   172 LKRSQSHLPYFTPKPP--QDSAVIKAGYCVKQGAVMKNWKRRYFQLDENTIGYFKSELEKEPLRV 234

  Fly   550 DGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPK 614
            ..:.:|:.:..........:.:.|::.|..:...|.|. ||...:||:..:..|
Human   235 IPLKEVHKVQECKQSDIMMRDNLFEIVTTSRTFYVQAD-SPEEMHSWIKAVSGA----------- 287

  Fly   615 QTDIEQDFIKAQLQQPSSSPVTPGTPAGPHFSSDEEYRTASEGGRRDSLDWGSPLSPSPPVLRSC 679
                    |.||.        .||..|....|.....:|.|.|.|:   .|          .|.|
Human   288 --------IVAQR--------GPGRSASSQSSMRLSAKTVSVGKRK---SW----------RRIC 323

  Fly   680 LRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETLRAEASLRE 744
            .|                                    ||..:....|.:.|:... .|.||.|.
Human   324 GR------------------------------------PEGCRTLVYRGIHQELVN-AARASPRS 351

  Fly   745 ARMSELLATLQRTEQQLTARLQEQQQQLNSELTQAKQSASDLMHNLGMQLTESQCQIKQLEDRLA 809
            .|:.....:.||:.:.||  .....|||                 .|:.|...:.:|.::.   .
Human   352 FRIQTRFPSYQRSHRHLT--FHSLSQQL-----------------FGLNLYHGEARILRVS---C 394

  Fly   810 QGIEENEGLYKRLRELQAQD 829
            ||         :.||||..|
Human   395 QG---------QARELQGPD 405

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	20/103 (19%)
		PH	509..603	CDD:278594	19/93 (20%)
		SbcC	726..1353	CDD:223496	24/104 (23%)
PLEKHA1	XP_011538319.1	PH1_TAPP1_2	1..117	CDD:270089	9/72 (13%)
		PH2_TAPP1_2	185..298	CDD:270090	29/142 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910