DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osp and dapp1

DIOPT Version :9

Sequence 1:	NP_001162975.1	Gene:	osp / 34850	FlyBaseID:	FBgn0003016	Length:	1566	Species:	Drosophila melanogaster
Sequence 2:	XP_031755425.1	Gene:	dapp1 / 548440	XenbaseID:	XB-GENE-482064	Length:	311	Species:	Xenopus tropicalis

Alignment Length:	332	Identity:	69/332 - (20%)
Similarity:	116/332 - (34%)	Gaps:	92/332 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 VETGEDVDEDEEDETSVPRK---SKTVSMGGQDEN-NRNAGNEITNRVSQPTTCLLIEDIRRDEK 339
            ||..| |:|||| ||.:..:   |...|:|....| :|:|...:.....|..:.||
Frog    52 VELAE-VEEDEE-ETELENQTADSGLSSLGWYHANLSRHAAEALLLTNGQDGSYLL--------- 105

  Fly   340 TIKDIANTITNLSQQQNKRWSTAVNNALNNQHHF-----GHHSQYQVTSRDETDFQMSSNSSSTK 399
                      ..|..::..:|.:| .|.::..||     |.:            |:...|...|.
Frog   106 ----------RNSNSKSNSYSLSV-RARDSVKHFEVLQCGSY------------FKFGFNEFPTL 147

  Fly   400 SQNPASERPKSLPLASNSTPAIVSAIVKKIPTVMEQGDKTKPTARLQLHLKSPKHYQHERGDPDG 464
            .|  ..|...:.||..:.:..::.                         ||.|  |.
Frog   148 KQ--FVEHFANQPLIGSESGTLIL-------------------------LKHP--YP-------- 175

  Fly   465 GCNLDELCVNYMAKTDELRSVGKANSKSSSGQGKPPVKEESLNAKKGWLMKQDNRTCEWSKHWFT 529
             |.::|..:....:.......|::.|      ...|| ..:|..|:|:|.||..|...|...||.
Frog   176 -CTVEEPSIYEAVRVHTAMQTGRSES------DLVPV-APALGTKEGYLTKQGGRVKSWKTRWFI 232

  Fly   530 LSGAALFYYRDPLCEERGVLDGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRN 594
            ||...|.|::|.|..|.   ...||:...::|..:.:..|.:.|.: .:..:...|.:.:.:..:
Frog   233 LSRNELKYFKDKLSTEP---IKTLDLTECSAVQFDYSQEKVNCFCM-VFPLRTYYLCAKTGAEAD 293

  Fly   595 SWLAVLR 601
            .|:.:||
Frog   294 EWIKMLR 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	25/93 (27%)
		PH	509..603	CDD:278594	25/93 (27%)
		SbcC	726..1353	CDD:223496
dapp1	XP_031755425.1	SH2_DAPP1_BAM32_like	73..164	CDD:198218	23/124 (19%)
dapp1	XP_031755425.1	PH_DAPP1	208..303	CDD:269977	26/97 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910