DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment osp and PHETA1

DIOPT Version :9

Sequence 1:	NP_001162975.1	Gene:	osp / 34850	FlyBaseID:	FBgn0003016	Length:	1566	Species:	Drosophila melanogaster
Sequence 2:	NP_001171467.1	Gene:	PHETA1 / 144717	HGNCID:	26509	Length:	262	Species:	Homo sapiens

Alignment Length:	267	Identity:	58/267 - (21%)
Similarity:	89/267 - (33%)	Gaps:	79/267 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   497 GKPP--------VKEESL-----------NAKKGWLMKQDNRTCEWSKHWFTLSGAALFYYRDPL 542
            |.||        :.|.||           ||  |:|.|:..|...:.:.||.|.|..|||:.|..
Human     4 GSPPGPAIATMKLNERSLAFYATCDAPVDNA--GFLYKKGGRHAAYHRRWFVLRGNMLFYFEDAA 66

  Fly   543 CEERGVLDGVLDVNSLTSVIPEPAASKQHAFQLTTWDKQRLVLASLSPSSRNSWLAVLRSAAGLP 607
            ..|.   .||:.:...|..:.|.|.....|.:......:..|||:.|..:...|:..|..|:
Human    67 SREP---VGVIILEGCTVELVEAAEEFAFAVRFAGTRARTYVLAAESQDAMEGWVKALSRAS--- 125

  Fly   608 QLDTPPKQTDIEQDFIKAQLQQPSSSPVTPGTPAGPHFSSDEEYRTASEGGRRDSLDWGSPLS-P 671
                        .|:::..:::.                  |:...|..||...:|....|.| |
Human   126 ------------FDYLRLVVREL------------------EQQLAAVRGGGGMALPQPQPQSLP 160

  Fly   672 SPPVLRSCLRNRSLASLHKRSRSSPPSSRRSTVDSVASDELPLLVVPEEMQPTESRELKQQCETL 736
            .||.|.|.|                     :.|.|:.|...|:..:|...:|:.....:..|...
Human   161 LPPSLPSAL---------------------APVPSLPSAPAPVPALPLPRRPSALPPKENGCAVW 204

  Fly   737 RAEASLR 743
            ..||:.|
Human   205 STEATFR 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	26/103 (25%)
		PH	509..603	CDD:278594	25/93 (27%)
		SbcC	726..1353	CDD:223496	4/18 (22%)
PHETA1	NP_001171467.1	PH_Ses	24..143	CDD:270105	30/156 (19%)
PHETA1	NP_001171467.1	PH	35..125	CDD:278594	25/92 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910