DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment osp and AgaP_AGAP000864

DIOPT Version :9

Sequence 1:	NP_001162975.1	Gene:	osp / 34850	FlyBaseID:	FBgn0003016	Length:	1566	Species:	Drosophila melanogaster
Sequence 2:	XP_003437123.1	Gene:	AgaP_AGAP000864 / 1277378	VectorBaseID:	AGAP000864	Length:	343	Species:	Anopheles gambiae

Alignment Length:	367	Identity:	82/367 - (22%)
Similarity:	140/367 - (38%)	Gaps:	98/367 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly   499 PPVKEESLNAKKGWLMKQDNRTCEWSKHWFTLSGAALFYY-----RDPLCEERGVLDGVLDVNSL 558
            |||..|      |||.|:......|.:.||.|.|..|||:     ::||        |::.:...
Mosquito    15 PPVDLE------GWLNKRGEMNKSWQRRWFVLKGNLLFYFEKRTDKEPL--------GMIILEGC 65

  Fly   559 TSVIPEPAASKQHAFQLTTW--DKQRLVLASLSPSSRNSWLAVLRSAAGLPQLDTPPKQTDIEQD 621
            |..:.|  .|:|:.||:...  :.:...|::.|.|:...|:..| :.||...:.....:...:.|
Mosquito    66 TVELAE--ESEQYCFQIIFHGPNNRTYYLSTESQSNMEQWMKAL-TCAGYDYMKLMVAELQRQLD 127

  Fly   622 FIKAQL--------------------QQPSSSPVTP--------GTPAGPHFSSDEEYRTAS--- 655
            .|:.|.                    |.|.:.|:|.        ||..|   .|::|.|..|
Mosquito   128 EIEGQCREKAPEMAPILAPPRAPPRRQNPFNKPLTTEYASNADIGTGGG---VSEKEQRGTSPPT 189

  Fly   656 ---EGGRRDSLDWGSPLSPSPPVLRSCLRNRSLASLHKRSRSSPPS-----SRRSTVDSV-ASDE 711
               ..||:      :|..|:|......:.:.::..:.|.|.|:.|:     ||::||.:. :||.
Mosquito   190 PLARTGRK------APAPPAPNTAAPTVHSPTVPDIGKLSPSADPTADGPVSRKATVTATKSSDA 248

  Fly   712 LPLLVVPEEMQPTESRELKQQCETLRAEASLREARMSELLATL---QRTEQQLTARLQEQQQQLN 773
            :..:...::.|    |.|::......:..::..|....:||.|   ..:.|:|.   |:||||..
Mosquito   249 IASMANGDQQQ----RPLERGSVASFSFEAMHSALGVPVLADLCKWNASRQELE---QQQQQQQE 306

  Fly   774 SELTQAKQSASDLMHNLGMQLTESQCQIKQLEDRLAQGIEEN 815
            .|....||...:.               ||.|......:::|
Mosquito   307 EEDNNRKQEEDNR---------------KQEESATVLNVDDN 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
osp	NP_001162975.1	PH_RIP	48..191	CDD:269942
		PH	85..185	CDD:278594
		PH_M-RIP	509..613	CDD:270094	28/110 (25%)
		PH	509..603	CDD:278594	26/100 (26%)
		SbcC	726..1353	CDD:223496	20/93 (22%)
AgaP_AGAP000864	XP_003437123.1	PH_Ses	11..129	CDD:270105	33/130 (25%)
AgaP_AGAP000864	XP_003437123.1	PH	17..107	CDD:278594	27/105 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910